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NCT01557738 · ClinicalTrials.gov registry record · NA
Role of Flavanols in Exercise and Aging
A NA study, sponsored by University of Texas at Austin.
- Completed
- Registry status
- NA
- Development phase
- 20
- Enrollment target
NCT01557738 is a NA study that has completed, run by University of Texas at Austin. The registered enrollment target is 20 participants.
The verdict
NCT01557738, a NA study, has completed, sponsored by University of Texas at Austin.
- COMPLETED
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
Study Summary
It has well known that diets rich in fruits, vegetables and cocoa products are associated with positive health benefits and these positive effects have been shown to be due to compounds they contain called flavanols. Flavanols have been shown to exert their positive effects by indirectly increasing nitric oxide (NO) bioavailability. NO is a potent vasodilator that is believed to play a role in increasing blood flow to active muscle during exercise. This regulatory process is impaired with healthy aging. The underlying premise to this study is that if NO bioavailability can be increased following flavanol ingestion, will there be a restoration of blood flow during exercise in older individuals? Accordingly, the first part of this research project will compare the acute vascular effects of flavanol ingestion between a young and old group. The investigators have hypothesized that both groups will show an improvement in blood flow to active muscle during exercise, though the magnitude of the change will be greater in the older group. The second part of this project will look at the effects of 4 weeks of daily flavanol ingestion in the old group. The investigators hypothesize that subjects will demonstrate an improvement in blood flow to active muscle during exercise after the 4 week intervention and that the magnitude of the change will be greater than the acute effects. Findings from this proposal will provide evidence for the efficacy of flavanols to be used (as a simple and safe lifestyle intervention) to reverse or combat impaired blood flow regulation in older individuals.
Interventions
- DIETARY_SUPPLEMENT High Flavanol Trial
- DIETARY_SUPPLEMENT Low Flavanol Trial
- DIETARY_SUPPLEMENT High Flavanol Trial; long-term
- DIETARY_SUPPLEMENT Low Flavanol Trial; long-term effects
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2012-12 |
| Est. Completion | 2014-04 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01557738
The ClinicalTrials.gov registry entry for NCT01557738 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Texas at Austin, which has 257 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which High Flavanol Trial is the first listed.
NCT01557738 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01557738 about?
NCT01557738 is a clinical study titled "Role of Flavanols in Exercise and Aging". It has well known that diets rich in fruits, vegetables and cocoa products are associated with positive health benefits and these positive effects have been shown to be due to compounds they contain called flavanols. Flavanols have been shown to exert their positive effects by indirectly increasing ...
What is the current status of trial NCT01557738?
This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2012-12. Estimated completion is 2014-04.
What interventions are being tested in trial NCT01557738?
The interventions under investigation include: High Flavanol Trial (DIETARY_SUPPLEMENT), Low Flavanol Trial (DIETARY_SUPPLEMENT), High Flavanol Trial; long-term (DIETARY_SUPPLEMENT), Low Flavanol Trial; long-term effects (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT01557738?
This trial is sponsored by University of Texas at Austin, which has 257 total clinical trials registered on ClinicalTrials.gov.
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