Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01556230 · ClinicalTrials.gov registry record
Prospective Study of Clinically Nonfunctioning Pituitary Adenomas
A clinical trial of Pituitary Adenoma and Pituitary Tumor, sponsored by Columbia University.
- Completed
- Registry status
- 292
- Enrollment target
- 1
- Study location
NCT01556230: Completed study of Pituitary Adenoma and Pituitary Tumor, sponsored by Columbia University.
NCT01556230 is a study of Pituitary Adenoma and Pituitary Tumor that has completed, run by Columbia University. The registered enrollment target is 292 participants, above the 256-participant average among 9 other Pituitary Adenoma trials with a reported enrollment target (14% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01556230, a study of Pituitary Adenoma and Pituitary Tumor, has completed, sponsored by Columbia University.
- COMPLETED
- Registry status
- 292 participants
- Enrollment target
- 1
- Study location
Study Summary
This project is the first comprehensive prospective study of clinically non-functioning pituitary adenomas (CNFAs). Two groups of subjects will be studied: Group I will consist of 100 patients with clinically non-functioning (CNF) pituitary lesions who are asymptomatic and do not require surgery; Group II will consist of 250 patients who have pituitary lesions that are symptomatic and require surgery. Patients will be followed with a series of endocrine laboratory testing, physical examinations, testing of quality of life and neurocognitive function before and serially over time either during non-surgical management or after surgery and in some patients before and after radiotherapy (RT). Data on pituitary magnetic resonance imaging (MRI) studies and visual field testing being done over time during follow up as part of clinical care will be collected.
Primary Outcome
Tumor enlargement over the study period
Conditions Studied
Interventions
- PROCEDURE Surgical intervention for CNFA
- RADIATION Radiotherapy for CNFA
Study Locations (1)
New York
- Columbia University Vagelos College of Physicians & Surgeons - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 292 participants |
| Start Date | 2010-11 |
| Est. Completion | 2024-06 |
What the finished NCT01556230 record still lists
NCT01556230 is an observational study that tracks outcomes without assigning an intervention. The registered 292 participants enrollment target is mid-sized for trials with a published cap, above the 256-participant average among 9 other Pituitary Adenoma trials with a reported enrollment target (14% higher).
The record links to 2 conditions, with Pituitary Adenoma appearing as the primary indexed condition, and to 2 interventions - of which Surgical intervention for CNFA is the first listed.
NCT01556230 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT01556230 about?
NCT01556230 is a clinical study titled "Prospective Study of Clinically Nonfunctioning Pituitary Adenomas". This project is the first comprehensive prospective study of clinically non-functioning pituitary adenomas (CNFAs). Two groups of subjects will be studied: Group I will consist of 100 patients with clinically non-functioning (CNF) pituitary lesions who are asymptomatic and do not require surgery; Gr...
What is the current status of trial NCT01556230?
This trial is currently completed. The enrollment target is 292 participants. The study started on 2010-11. Estimated completion is 2024-06.
What conditions does trial NCT01556230 study?
This clinical trial studies the following conditions: Pituitary Adenoma, Pituitary Tumor.
What interventions are being tested in trial NCT01556230?
The interventions under investigation include: Surgical intervention for CNFA (PROCEDURE), Radiotherapy for CNFA (RADIATION).
Who is sponsoring clinical trial NCT01556230?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01556230 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pituitary Adenoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01556230's enrollment target sits among peer trials
292 3rd of 9 higher than 7 of 9 other Pituitary Adenoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pituitary Adenoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Prophylactic Oral Antibiotics on Sinonasal Outcomes Following Endoscopic Transsphenoidal Surgery for Pituitary Lesions
RECRUITING · Phase 4
-
Evaluation of Intraoperative Contrast Enhanced Ultrasound for the Identification of Pituitary Adenoma in Cushing's Disease Compared to Other Pituitary Tumors
RECRUITING
-
DDAVP for Pituitary Adenoma
RECRUITING · NA
-
68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors.
RECRUITING · Phase 4
-
Use of [18F] Fluoroethyl-L-tyrosine PET/MRI for Identifying Small Functional Pituitary Adenomas
RECRUITING · Phase 1
-
A First in Human Study Using 89Zr-cRGDY Ultrasmall Silica Particle Tracers for Malignant Brain Tumors
ACTIVE NOT RECRUITING · Phase 1
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04429542 · 292 participants · Phase 1
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
- NCT05406622 · 292 participants · NA
MOTIV BTK Randomized Controlled Trial
- NCT05757102 · 292 participants · Phase 3
A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma
- NCT06569667 · 292 participants · NA
Using AI and Peer Coaching to Address Racial Disparities Among People Who Use Opioids
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia