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BAsel Syncope EvaLuation (BASEL IX) Study
NCT01548352 · View on ClinicalTrials.gov ↗
Study Summary
Syncope is a major health problem. In the emergency department (ED), the management of patients with syncope still remains a clinical challenge because underlying diseases and prognosis can be extremely various. Structural heart disease and primary electrical disorders are major risk factors for sudden cardiac death and mortality in patients with syncope. In contrast, patients with reflex syncope and exclusion of structural heart disease have an excellent prognosis. Therefore The investigators test the hypothesis that the use of a meticulous patient history, clinical examination and novel biomarkers can improve the rapid and accurate diagnosis of cardiac syncope in patients presenting to the ED and is able to improve risk stratification regarding adverse outcomes. The prospective multicenter cohort study is designed to enroll 720 patients presenting with transient loss of consciousness within the last 12 hours to the ED. Blood samples for the measurement of novel biomarkers will be obtained at presentation. All patients will be contacted by phone at 6, 12 and 24 months to determine major adverse events (death, resuscitation, recurrence of syncope, hospitalization for syncope).
Conditions Studied
Study Locations (15)
Other
- Instituto Cardiovascular de Buenos Aires — Buenos Aires
- Royal Brisbane and Women's hospital — Brisbane
- Sant'Andrea Hospital — Rome
- Christchurch Hospital — Christchurch
- Medical University of Silesia — Zabrze
- Hospital del Mar — Barcelona
- Hospital Clinic of Barcelona — Barcelona
- Hospital Universitario Clínico San Carlos — Madrid
- University Hospital Basel — Basel
- Luzern Kantonsspital — Lucerne
- University Hospital Zurich — Zurich
Texas
- Baylor College of Medicine — Houston
Bavaria
- Klinikum Nürnberg — Nuremberg
Basel-Landschaft
- Kantonsspital Baselland — Liestal
Canton of Schwyz
- Spital Lachen — Lachen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3,500 participants |
| Start Date | 2010-04 |
| Est. Completion | 2025-12 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01548352
The ClinicalTrials.gov registry entry for NCT01548352 describes a study currently listed as active not recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 3,500 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University Hospital, Basel, Switzerland, which has 10 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Syncope appearing as the primary indexed condition, and to 0 interventions. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT01548352 reports 15 study locations spanning 5 distinct geographic areas — top geographies include Other, Texas, Bavaria. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT01548352 about?
NCT01548352 is a clinical study titled "BAsel Syncope EvaLuation (BASEL IX) Study". Syncope is a major health problem. In the emergency department (ED), the management of patients with syncope still remains a clinical challenge because underlying diseases and prognosis can be extremely various. Structural heart disease and primary electrical disorders are major risk factors for sud...
What is the current status of trial NCT01548352?
This trial is currently active not recruiting. The enrollment target is 3,500 participants. The study started on 2010-04. Estimated completion is 2025-12.
What conditions does trial NCT01548352 study?
This clinical trial studies the following conditions: Syncope. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
Who is sponsoring clinical trial NCT01548352?
This trial is sponsored by University Hospital, Basel, Switzerland, which has 10 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT01548352 being conducted?
This trial has 15 study locations across Texas, Bavaria, Basel-Landschaft, Canton of Schwyz. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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