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NCT01547117 · ClinicalTrials.gov registry record · NA
Dietary Salt in Postural Tachycardia Syndrome
A NA study, sponsored by Vanderbilt University.
- Completed
- Registry status
- NA
- Development phase
- 38
- Enrollment target
NCT01547117: Completed NA study, sponsored by Vanderbilt University.
NCT01547117 is a NA study that has completed, run by Vanderbilt University. The registered enrollment target is 38 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01547117, a NA study, has completed, sponsored by Vanderbilt University.
- COMPLETED
- Registry status
- NA
- Development phase
- 38 participants
- Enrollment target
Study Summary
Patients with POTS may not adequately expand their plasma volume in response to a high-sodium (Na+) diet. Mechanisms involved in the regulation of plasma volume, such as the renin-angiotensin-aldosterone system and renal dopamine, may be impaired in POTS and may respond inappropriately to changes in dietary sodium.The purpose of this study is to determine (1) whether a high dietary sodium level appropriately expands plasma volume in POTS; (2) whether plasma renin activity and aldosterone are modified appropriately by changes in dietary sodium in POTS; and (3) whether patients with POTS have improvements in their orthostatic tachycardia and symptoms as a result of a high dietary sodium level.
Primary Outcome
Plasma volume (PV) was determined by the indicator tracer-dilution technique, using the DAXOR Blood Volume Analyzer (BVA)-100 system (DAXOR Corporation), on Day 7 of the low sodium and high sodium dietary interventions. Outcome data are the absolute values for PV on Day 7 for each diet.
Interventions
- PROCEDURE Exercise Capacity Test - Bicycle
- PROCEDURE Posture Study
- RADIATION Blood Volume
- RADIATION Total Blood Volume
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 38 participants |
| Start Date | 2012-03 |
| Est. Completion | 2021-12 |
| Phase | NA |
What the finished NCT01547117 record still lists
NCT01547117 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 38 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 4 interventions - of which Exercise Capacity Test - Bicycle is the first listed.
NCT01547117 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01547117 about?
NCT01547117 is a clinical study titled "Dietary Salt in Postural Tachycardia Syndrome". Patients with POTS may not adequately expand their plasma volume in response to a high-sodium (Na+) diet. Mechanisms involved in the regulation of plasma volume, such as the renin-angiotensin-aldosterone system and renal dopamine, may be impaired in POTS and may respond inappropriately to changes in...
What is the current status of trial NCT01547117?
This trial is currently completed. It is a NA study. The enrollment target is 38 participants. The study started on 2012-03. Estimated completion is 2021-12.
What interventions are being tested in trial NCT01547117?
The interventions under investigation include: Exercise Capacity Test - Bicycle (PROCEDURE), Posture Study (PROCEDURE), Blood Volume (RADIATION), Total Blood Volume (RADIATION).
Who is sponsoring clinical trial NCT01547117?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01547117's enrollment target sits among peer trials
38 1538th of 2000 higher than 461 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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