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NCT01543074 · ClinicalTrials.gov registry record · NA
Dietary Histone Deacetylase Inhibitors (HDAC)
A NA study, sponsored by Texas A&M University.
- Terminated
- Registry status
- NA
- Development phase
- 23
- Enrollment target
NCT01543074: Clinical Trial NA study, sponsored by Texas A&M University.
NCT01543074 is a NA study that was terminated before completion, run by Texas A&M University. The registered enrollment target is 23 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01543074, a NA study, was terminated before completion, sponsored by Texas A&M University.
- TERMINATED
- Registry status
- NA
- Development phase
- 23 participants
- Enrollment target
Study Summary
This pilot, three-week study will help scientists understand more about how the foods people eat can modify histone deacetylases, enzymes the body produces naturally. Broccoli sprout extract (BSE) and garlic oil are thought to modify these enzymes. The purpose of this study is to see if taking broccoli sprout extract alone, garlic oil alone, or broccoli sprout extract and garlic oil together, can decrease the action of histone deacetylase (HDAC) and turn on genes in white blood cells. There will be 80 people in this study.
Primary Outcome
The levels of "Sulforaphane and its metabolites (combined)" in blood was measured using Liquid Chromatrography-Mass Spectrometry (LC-MS) methods. Cmax (mean +/- SD) values are shown in the "Outcome Measure Data Table".
Interventions
- DIETARY_SUPPLEMENT BSE placebo
- DIETARY_SUPPLEMENT Garlic oil
- DRUG BSE
- DIETARY_SUPPLEMENT Garlic Oil Placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2013-02 |
| Est. Completion | 2013-12 |
| Phase | NA |
Why NCT01543074 stopped before completion
NCT01543074 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 4 interventions - of which BSE placebo is the first listed.
NCT01543074 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01543074 about?
NCT01543074 is a clinical study titled "Dietary Histone Deacetylase Inhibitors (HDAC)". This pilot, three-week study will help scientists understand more about how the foods people eat can modify histone deacetylases, enzymes the body produces naturally. Broccoli sprout extract (BSE) and garlic oil are thought to modify these enzymes. The purpose of this study is to see if taking brocc...
What is the current status of trial NCT01543074?
This trial is currently terminated. It is a NA study. The enrollment target is 23 participants. The study started on 2013-02. Estimated completion is 2013-12.
What interventions are being tested in trial NCT01543074?
The interventions under investigation include: BSE placebo (DIETARY_SUPPLEMENT), Garlic oil (DIETARY_SUPPLEMENT), BSE (DRUG), Garlic Oil Placebo (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT01543074?
This trial is sponsored by Texas A&M University, which has 95 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01543074's enrollment target sits among peer trials
23 1755th of 2000 higher than 245 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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