Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01542307 · ClinicalTrials.gov registry record · Phase 2
Normobaric Oxygen (NBO) Therapy in Acute Migraine
A Phase 2 study, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- Phase 2
- Development phase
- 22
- Enrollment target
NCT01542307: Completed Phase 2 study, sponsored by Massachusetts General Hospital.
NCT01542307 is a Phase 2 study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 22 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01542307, a Phase 2 study, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 22 participants
- Enrollment target
Study Summary
This is a pilot study investigating the therapeutic potential of breathing 100% oxygen in acute migraine headache.
Primary Outcome
The mean change in VAS pain scores from 0 minutes to 30 minutes was selected as the primary outcome measure. The VAS scale has a range from 0-10 with higher scores indicating greater severity of symptoms.
Interventions
- BIOLOGICAL Oxygen
- BIOLOGICAL Room air
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2012-07 |
| Est. Completion | 2015-09 |
| Phase | Phase 2 |
What the finished NCT01542307 record still lists
NCT01542307 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 2 interventions - of which Oxygen is the first listed.
NCT01542307 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01542307 about?
NCT01542307 is a clinical study titled "Normobaric Oxygen (NBO) Therapy in Acute Migraine". This is a pilot study investigating the therapeutic potential of breathing 100% oxygen in acute migraine headache.
What is the current status of trial NCT01542307?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 22 participants. The study started on 2012-07. Estimated completion is 2015-09.
What interventions are being tested in trial NCT01542307?
The interventions under investigation include: Oxygen (BIOLOGICAL), Room air (BIOLOGICAL).
Who is sponsoring clinical trial NCT01542307?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01542307's enrollment target sits among peer trials
22 1790th of 2000 higher than 207 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02508038 · 22 participants · Phase 1
Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors
- NCT03099356 · 22 participants · Phase 2
Cyclophosphamide and Sirolimus for the Treatment of Metastatic, RAI-refractory, Differentiated Thyroid Cancer
- NCT03676647 · 22 participants
Diagnostic DNA Methylation Signature in Diagnosing Thyroid Cancer After Fine-Needle Aspiration in Patients With Thyroid Nodules
- NCT04569591 · 22 participants · NA
DDAVP for Pituitary Adenoma
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia