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NCT01535807 · ClinicalTrials.gov registry record · NA

CorMatrix ECM Study: To Identify Inflammatory Markers Following CABG With/Without ECM

A NA study, sponsored by Inova Health Care Services.

Terminated
Registry status
NA
Development phase
44
Enrollment target

NCT01535807: Clinical Trial NA study, sponsored by Inova Health Care Services.

NCT01535807 is a NA study that was terminated before completion, run by Inova Health Care Services. The registered enrollment target is 44 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01535807, a NA study, was terminated before completion, sponsored by Inova Health Care Services.

TERMINATED
Registry status
NA
Development phase
44 participants
Enrollment target

Study Summary

The objective of this study is to identify proteomic inflammatory biomarkers to determine if there are differences in the biomarkers in patients who are treated using the CorMatrix ECM implant to close the pericardium and the patients whose pericardium is left open (the current standard of care).

Primary Outcome

Percentage change in Inflammatory Cytokine Levels in serum derived from participant blood sample that underwent novel nanoparticle-based biomarker harvesting technology to capture and isolate global low molecular weight (LMW) proteome. Peptides from captured proteomes are detected with reversed-phase liquid chromatography/electrospray tandem mass spectrometry (LC-MS/MS). Inflammatory cytokines include Interleukin 6 (IL6), Interleukin 8 (IL8), Interleukin 2 Receptor (IL2R), Tumor Necrosis Factor

Interventions

  • DEVICE CorMatrix extra cellular matrix (ECM)

Trial Details

FieldValue
Enrollment Target 44 participants
Start Date 2012-01
Est. Completion 2016-06
Phase NA
Inova Health Care Services

75 total trials

Why NCT01535807 stopped before completion

NCT01535807 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 1 intervention - of which CorMatrix extra cellular matrix (ECM) is the first listed.

NCT01535807 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01535807 about?

NCT01535807 is a clinical study titled "CorMatrix ECM Study: To Identify Inflammatory Markers Following CABG With/Without ECM". The objective of this study is to identify proteomic inflammatory biomarkers to determine if there are differences in the biomarkers in patients who are treated using the CorMatrix ECM implant to close the pericardium and the patients whose pericardium is left open (the current standard of care).

What is the current status of trial NCT01535807?

This trial is currently terminated. It is a NA study. The enrollment target is 44 participants. The study started on 2012-01. Estimated completion is 2016-06.

What interventions are being tested in trial NCT01535807?

The interventions under investigation include: CorMatrix extra cellular matrix (ECM) (DEVICE).

Who is sponsoring clinical trial NCT01535807?

This trial is sponsored by Inova Health Care Services, which has 75 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01535807's enrollment target sits among peer trials

44 1423rd of 2000 higher than 566 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01535807, the US trial registry maintained by the National Library of Medicine. NCT01535807 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.