Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01529788 · ClinicalTrials.gov registry record · Phase 4
Onabotulinum Toxin Type A and Abobotulinum Toxin Type A Crow's Feet Rhytid Study
A Phase 4 study of Intrinsic Aging of Skin and Solar Elastosis, sponsored by The Maas Clinic.
- Completed
- Registry status
- Phase 4
- Development phase
- 90
- Enrollment target
- 1
- Study location
NCT01529788: Completed Phase 4 study of Intrinsic Aging of Skin and Solar Elastosis, sponsored by The Maas Clinic.
NCT01529788 is a Phase 4 study of Intrinsic Aging of Skin and Solar Elastosis that has completed, run by The Maas Clinic. The registered enrollment target is 90 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01529788, a Phase 4 study of Intrinsic Aging of Skin and Solar Elastosis, has completed, sponsored by The Maas Clinic.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 90 participants
- Enrollment target
- 1
- Study location
Study Summary
The objective of the study is to compare the time to onset of Dysport® versus Botox® in the treatment of lateral orbital rhytids ("crow's feet"). Thirty subjects were enrolled in the study; specifically 30 male or female patients 18 years or older with moderate to severe lateral orbital rhytids at maximum contracture. Each patient were randomized to be treated with Dysport® on one side and Botox® on the other side. Both the injector and patient were blinded to the injected toxin. The efficacy endpoints were determined by investigator and subject live assessment of "crow's feet" at rest and maximum contraction at each visit (every other day for 6 days post-injection, every month for 9 months following) using a validated 5 point photographic scale(no wrinkles \[0\], very fine wrinkles \[1\], fine wrinkles \[2\], moderate wrinkles \[3\] or severe wrinkles \[4\]) used in previous studies. A written description of each photograph was included to help standardize the application of the Photographic Scale.
Primary Outcome
Subject and investigator assessed grading as well as subject preference
Conditions Studied
Interventions
- DRUG Right lateral orbital injection of Botox Cosmetic or Dysport
- DRUG Left lateral orbital injection of Botox Cosmetic or Dysport
Study Locations (1)
California
- The Maas Clinic - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2009-09 |
| Est. Completion | 2014-09 |
| Phase | Phase 4 |
What the finished NCT01529788 record still lists
NCT01529788 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (83% lower).
The record links to 2 conditions, with Intrinsic Aging of Skin appearing as the primary indexed condition, and to 2 interventions - of which Right lateral orbital injection of Botox Cosmetic or Dysport is the first listed.
NCT01529788 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT01529788 about?
NCT01529788 is a clinical study titled "Onabotulinum Toxin Type A and Abobotulinum Toxin Type A Crow's Feet Rhytid Study". The objective of the study is to compare the time to onset of Dysport® versus Botox® in the treatment of lateral orbital rhytids ("crow's feet"). Thirty subjects were enrolled in the study; specifically 30 male or female patients 18 years or older with moderate to severe lateral orbital rhytids at m...
What is the current status of trial NCT01529788?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 90 participants. The study started on 2009-09. Estimated completion is 2014-09.
What conditions does trial NCT01529788 study?
This clinical trial studies the following conditions: Intrinsic Aging of Skin, Solar Elastosis.
What interventions are being tested in trial NCT01529788?
The interventions under investigation include: Right lateral orbital injection of Botox Cosmetic or Dysport (DRUG), Left lateral orbital injection of Botox Cosmetic or Dysport (DRUG).
Who is sponsoring clinical trial NCT01529788?
This trial is sponsored by The Maas Clinic, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01529788 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Intrinsic Aging of Skin
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01529788's enrollment target sits among peer trials
90 886th of 2000 higher than 1,089 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02521311 · 90 participants · Phase 2
Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)
- NCT02939573 · 90 participants · Phase 2
A Randomized Multicenter Study for Isolated Skin Vasculitis
- NCT03128879 · 90 participants · Phase 2
Venetoclax With Ibrutinib or Acalabrutinib in Pts. With High-risk CLL
- NCT03184038 · 90 participants · NA
Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia