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NCT01522768 · ClinicalTrials.gov registry record · Phase 2

Afatinib and Paclitaxel in Patients With Advanced HER2-Positive Trastuzumab-Refractory Advanced Esophagogastric Cancer

A Phase 2 study, sponsored by Memorial Sloan Kettering Cancer Center.

Completed
Registry status
Phase 2
Development phase
42
Enrollment target

NCT01522768: Completed Phase 2 study, sponsored by Memorial Sloan Kettering Cancer Center.

NCT01522768 is a Phase 2 study that has completed, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 42 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01522768, a Phase 2 study, has completed, sponsored by Memorial Sloan Kettering Cancer Center.

COMPLETED
Registry status
Phase 2
Development phase
42 participants
Enrollment target

Study Summary

The purpose of this study is to find out what effects, good or bad, the combination of standard chemotherapy agent paclitaxel with the investigational (experimental) drug afatinib that targets HER2, has on HER2-positive esophagogastric cancer that started to get bigger despite previous treatment with trastuzumab. The doctors will also study the tumor to understand why it grew while on trastuzumab treatment and to see the effects afatinib and paclitaxel has on the tumor.

Interventions

  • DRUG Afatinib and Paclitaxel

Trial Details

FieldValue
Enrollment Target 42 participants
Start Date 2012-03
Est. Completion 2023-02-20
Phase Phase 2

Sponsor

Memorial Sloan Kettering Cancer Center

1,884 total trials

What the Registry Record Tells You About NCT01522768

The ClinicalTrials.gov registry entry for NCT01522768 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 42 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Afatinib and Paclitaxel is the first listed.

NCT01522768 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01522768 about?

NCT01522768 is a clinical study titled "Afatinib and Paclitaxel in Patients With Advanced HER2-Positive Trastuzumab-Refractory Advanced Esophagogastric Cancer". The purpose of this study is to find out what effects, good or bad, the combination of standard chemotherapy agent paclitaxel with the investigational (experimental) drug afatinib that targets HER2, has on HER2-positive esophagogastric cancer that started to get bigger despite previous treatment wit...

What is the current status of trial NCT01522768?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 42 participants. The study started on 2012-03. Estimated completion is 2023-02-20.

What interventions are being tested in trial NCT01522768?

The interventions under investigation include: Afatinib and Paclitaxel (DRUG).

Who is sponsoring clinical trial NCT01522768?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.