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NCT01522248 · ClinicalTrials.gov registry record · NA

Early Immune Responses to Inactivated Influenza Vaccine: a Pilot Study

A NA study, sponsored by Johns Hopkins Bloomberg School of Public Health.

Completed
Registry status
NA
Development phase
20
Enrollment target

NCT01522248: Completed NA study, sponsored by Johns Hopkins Bloomberg School of Public Health.

NCT01522248 is a NA study that has completed, run by Johns Hopkins Bloomberg School of Public Health. The registered enrollment target is 20 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01522248, a NA study, has completed, sponsored by Johns Hopkins Bloomberg School of Public Health.

COMPLETED
Registry status
NA
Development phase
20 participants
Enrollment target

Study Summary

Some people experience symptoms just after receiving the seasonal inactivated influenza vaccine. The cause of some of these symptoms is likely to be an immune response to the vaccine. The investigators would like to look at the earliest immune responses to the inactivated influenza vaccine. This pilot study will help us to determine at what time points we should look.

Primary Outcome

This was an exploratory trial to look at the kinetics of early cytokine response to influenza vaccine. Serum collected was assessed for cytokines, and PBMCs may be assessed for innate and adaptive immune responses, as well as for genetic markers associated with immune responses to vaccination. Data for Cohort 1 reported as 0 hours and 24 hours. Data for Cohort 2 reported as 0 hours and 16 hours. Data was combined for the Cohorts and reported as 0 hours (baseline) and 14 days.

Interventions

  • BIOLOGICAL Trivalent Inactivated Influenza vaccine

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2012-01
Est. Completion 2012-02
Phase NA

What the finished NCT01522248 record still lists

NCT01522248 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which Trivalent Inactivated Influenza vaccine is the first listed.

NCT01522248 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01522248 about?

NCT01522248 is a clinical study titled "Early Immune Responses to Inactivated Influenza Vaccine: a Pilot Study". Some people experience symptoms just after receiving the seasonal inactivated influenza vaccine. The cause of some of these symptoms is likely to be an immune response to the vaccine. The investigators would like to look at the earliest immune responses to the inactivated influenza vaccine. This pil...

What is the current status of trial NCT01522248?

This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2012-01. Estimated completion is 2012-02.

What interventions are being tested in trial NCT01522248?

The interventions under investigation include: Trivalent Inactivated Influenza vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT01522248?

This trial is sponsored by Johns Hopkins Bloomberg School of Public Health, which has 187 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01522248's enrollment target sits among peer trials

20 1768th of 2000 higher than 140 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01522248, the US trial registry maintained by the National Library of Medicine. NCT01522248 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.