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NCT01521728 · ClinicalTrials.gov registry record · NA
Trial of Resistance and Endurance Exercise in Amyotrophic Lateral Sclerosis (ALS)
A NA study, sponsored by Johns Hopkins University.
- Completed
- Registry status
- NA
- Development phase
- 60
- Enrollment target
NCT01521728: Completed NA study, sponsored by Johns Hopkins University.
NCT01521728 is a NA study that has completed, run by Johns Hopkins University. The registered enrollment target is 60 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01521728, a NA study, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
Study Summary
The first questions asked by patients with a new diagnosis of Amyotrophic Lateral Sclerosis (ALS) often include: "Does exercise help slow the progression of the disease?", "Is there any harm in exercising?", or "What type of exercise (endurance or resistance) is most appropriate?" At this time, however, there is a lack of answers for people who suffer from an illness that affects their strength above all else. Yet the beneficial effects of exercise in both healthy people as well as people with other diseases have been extensively studied and resulted in recommendations about the types of exercise that are beneficial. In this study the investigators will ask participants with ALS to exercise in one of three ways: weightlifting (resistance exercise), stationary bicycling (endurance exercise), and range of motion exercise (the current "standard of care" for ALS patients). The investigators will use several different types of tests to determine whether one type of exercise is tolerated better and is safer than another. The investigators will also collect information about how the body responds to exercise in ALS. This study will help in the development of a larger national study to understand how exercise can be combined with other treatments to potentially improve strength and alter the course of the disease.
Primary Outcome
Evaluate the tolerability of RESISTANCE exercise in ALS subjects as measured by their ability to complete a 6 month study of a resistance exercise regimen.
Interventions
- OTHER Endurance Exercise
- OTHER Resistance Exercise
- OTHER Stretching/Range-of-Motion
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2012-01 |
| Est. Completion | 2016-02 |
| Phase | NA |
What the finished NCT01521728 record still lists
NCT01521728 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 3 interventions - of which Endurance Exercise is the first listed.
NCT01521728 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01521728 about?
NCT01521728 is a clinical study titled "Trial of Resistance and Endurance Exercise in Amyotrophic Lateral Sclerosis (ALS)". The first questions asked by patients with a new diagnosis of Amyotrophic Lateral Sclerosis (ALS) often include: "Does exercise help slow the progression of the disease?", "Is there any harm in exercising?", or "What type of exercise (endurance or resistance) is most appropriate?" At this time, howe...
What is the current status of trial NCT01521728?
This trial is currently completed. It is a NA study. The enrollment target is 60 participants. The study started on 2012-01. Estimated completion is 2016-02.
What interventions are being tested in trial NCT01521728?
The interventions under investigation include: Endurance Exercise (OTHER), Resistance Exercise (OTHER), Stretching/Range-of-Motion (OTHER).
Who is sponsoring clinical trial NCT01521728?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01521728's enrollment target sits among peer trials
60 1164th of 2000 higher than 745 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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