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NCT01519765 · ClinicalTrials.gov registry record · Phase 4
Buccal Versus Vaginal Misoprostol for Third Trimester Induction of Labor
A Phase 4 study, sponsored by University of California, Los Angeles.
- Terminated
- Registry status
- Phase 4
- Development phase
- 73
- Enrollment target
NCT01519765 is a Phase 4 study that was terminated before completion, run by University of California, Los Angeles. The registered enrollment target is 73 participants.
The verdict
NCT01519765, a Phase 4 study, was terminated before completion, sponsored by University of California, Los Angeles.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 73 participants
- Enrollment target
Study Summary
Approximately 22% of term pregnancies are induced. Misoprostol, a prostaglandin E1 analogue, is a widely accepted induction agent, that has been proven safe and effective for induction of labor. It stimulates both cervical ripening and uterine contractions, thus making it an ideal induction agent for unfavorable cervices. Research has examined the pharmacokinetics of different administration routes and effects on uterine contractility, side effects, and safety. Vaginal misoprostol has been shown to be superior over oral administration however patients often prefer a more tolerable route. Buccal administration has already been shown to be as effective as vaginal misoprostol for cervical ripening and induction in both first trimester and second trimester abortions. There is minimal research comparing buccal versus vaginal for third trimester induction of labor. The investigators study is a prospective, double blinded, randomized control trial comparing vaginal misoprostol and buccal misoprostol in equal dosages of 25 mcg. The investigators seek to answer the question whether buccal misoprostol is as effective as vaginal misoprostol for third trimester induction of labor.
Interventions
- DRUG Buccal Misoprostol
- DRUG Vaginal misoprostol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 73 participants |
| Start Date | 2011-07 |
| Est. Completion | 2014-12 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01519765
The ClinicalTrials.gov registry entry for NCT01519765 describes a study currently listed as terminated, categorized as Phase 4. The registered enrollment target is 73 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, Los Angeles, which has 897 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Buccal Misoprostol is the first listed.
NCT01519765 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01519765 about?
NCT01519765 is a clinical study titled "Buccal Versus Vaginal Misoprostol for Third Trimester Induction of Labor". Approximately 22% of term pregnancies are induced. Misoprostol, a prostaglandin E1 analogue, is a widely accepted induction agent, that has been proven safe and effective for induction of labor. It stimulates both cervical ripening and uterine contractions, thus making it an ideal induction agent fo...
What is the current status of trial NCT01519765?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 73 participants. The study started on 2011-07. Estimated completion is 2014-12.
What interventions are being tested in trial NCT01519765?
The interventions under investigation include: Buccal Misoprostol (DRUG), Vaginal misoprostol (DRUG).
Who is sponsoring clinical trial NCT01519765?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
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