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NCT01516905 · ClinicalTrials.gov registry record
PET/CT Imaging of Malignant Brain Tumors With 124I-NM404
A clinical trial, sponsored by University of Wisconsin, Madison.
- Completed
- Registry status
- 19
- Enrollment target
NCT01516905: Completed study, sponsored by University of Wisconsin, Madison.
NCT01516905 is a clinical trial that has completed, run by University of Wisconsin, Madison. The registered enrollment target is 19 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01516905 has completed, sponsored by University of Wisconsin, Madison.
- COMPLETED
- Registry status
- 19 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate diagnostic imaging techniques using 124I-NM404 PET/CT in humans with brain metastases and GBMs. This goal will be accomplished by determining the optimal PET/CT protocol and comparing PET tumor uptake to MRI and calculating tumor dosimetry. A future aim of this study will be to compare non-invasive PET/CT and MRI findings with pathological specimens, which is the gold standard but is invasive and impractical in many cases, to determine the sensitivity and specificity of both techniques for accurately detecting tumor infiltration. The data obtained from this study will be used to develop larger diagnostic and therapeutic trials in brain tumors. The long-term goals of this research are to improve the diagnosis and treatment of malignant brain tumors by using radioiodinated NM404.
Primary Outcome
patients will be imaged at 3 different times out to 48 hrs post injection. Images will be evaluated based on tumor/background, dimensions/volumes and a qualitative score
Interventions
- DRUG NM404
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2011-12 |
| Est. Completion | 2016-05-17 |
What the finished NCT01516905 record still lists
NCT01516905 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 19 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which NM404 is the first listed.
NCT01516905 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01516905 about?
NCT01516905 is a clinical study titled "PET/CT Imaging of Malignant Brain Tumors With 124I-NM404". The purpose of this study is to evaluate diagnostic imaging techniques using 124I-NM404 PET/CT in humans with brain metastases and GBMs. This goal will be accomplished by determining the optimal PET/CT protocol and comparing PET tumor uptake to MRI and calculating tumor dosimetry. A future aim of th...
What is the current status of trial NCT01516905?
This trial is currently completed. The enrollment target is 19 participants. The study started on 2011-12. Estimated completion is 2016-05-17.
What interventions are being tested in trial NCT01516905?
The interventions under investigation include: NM404 (DRUG).
Who is sponsoring clinical trial NCT01516905?
This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.
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