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NCT01505933 · ClinicalTrials.gov registry record · Phase 2
Airway Dimension Study in Children Undergoing MRI Sedated With Propofol and Dexmedetomidine
A Phase 2 study, sponsored by Milton S. Hershey Medical Center.
- Terminated
- Registry status
- Phase 2
- Development phase
- 24
- Enrollment target
NCT01505933: Clinical Trial Phase 2 study, sponsored by Milton S. Hershey Medical Center.
NCT01505933 is a Phase 2 study that was terminated before completion, run by Milton S. Hershey Medical Center. The registered enrollment target is 24 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01505933, a Phase 2 study, was terminated before completion, sponsored by Milton S. Hershey Medical Center.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 24 participants
- Enrollment target
Study Summary
Sedation is required in infants and children to successfully complete MRI while maintaining respiratory and hemodynamic stability. Limited access to the patient may pose a safety risk during MRI examination. Therefore, appropriate drugs need to be selected, administered, and titrated to achieve these objectives. Propofol is commonly used for sedation in children in the MRI setting because of its predictability, rapid onset, and offset of action. Dexmedetomidine has sedative and analgesic properties without affecting cardiovascular and respiratory stability. The rationale of this research is to assess the effect of these drugs on the upper airway and validate their use in children with upper airway disorders.
Primary Outcome
At each anatomic level, measurements will be obtained during three successive respiratory cycles and values will be averaged.
Interventions
- DRUG Dexmedetomidine
- DRUG propofol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2012-02 |
| Est. Completion | 2019-04-30 |
| Phase | Phase 2 |
Why NCT01505933 stopped before completion
NCT01505933 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (82% lower).
The record links to 0 conditions, and to 2 interventions - of which Dexmedetomidine is the first listed.
NCT01505933 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01505933 about?
NCT01505933 is a clinical study titled "Airway Dimension Study in Children Undergoing MRI Sedated With Propofol and Dexmedetomidine". Sedation is required in infants and children to successfully complete MRI while maintaining respiratory and hemodynamic stability. Limited access to the patient may pose a safety risk during MRI examination. Therefore, appropriate drugs need to be selected, administered, and titrated to achieve thes...
What is the current status of trial NCT01505933?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 2012-02. Estimated completion is 2019-04-30.
What interventions are being tested in trial NCT01505933?
The interventions under investigation include: Dexmedetomidine (DRUG), propofol (DRUG).
Who is sponsoring clinical trial NCT01505933?
This trial is sponsored by Milton S. Hershey Medical Center, which has 396 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01505933's enrollment target sits among peer trials
24 1756th of 2000 higher than 217 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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