Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01504802 · ClinicalTrials.gov registry record
Pharmacodynamics of CNP During Growth Hormone Treatment
A clinical trial, sponsored by Nemours Children's Clinic.
- Completed
- Registry status
- 22
- Enrollment target
NCT01504802 is a clinical trial that has completed, run by Nemours Children's Clinic. The registered enrollment target is 22 participants.
The verdict
NCT01504802 has completed, sponsored by Nemours Children's Clinic.
- COMPLETED
- Registry status
- 22 participants
- Enrollment target
Study Summary
It is now widespread practice to treat children with short stature with growth hormone. However, how an individual child will respond to growth hormone treatment is unpredictable and highly variable. Some children will not respond to growth hormone treatment at all. Currently, the only way to determine how well growth hormone therapy is working is to wait until they have been treated for six months and to compare the pre-treatment growth velocity with the growth velocity on treatment. It would be helpful to have a blood test that could be done shortly after starting growth hormone that could predict whether how well a child is responding to treatment. Such a blood test would allow endocrinologists to adjust the growth hormone dose (or possibly stop it altogether, if it is not working) long before the six months it currently takes. C-type natriuretic peptide (CNP) and its partner amino-terminal propeptide of CNP (NTproCNP) are proteins that play a critical role in regulating growth. The investigators have previously shown that blood levels of these proteins increase in children being treated with growth hormone. The investigators believe that a blood test for these proteins will be useful in predicting a child's response to growth hormone treatment. The purpose of this study is to determine when after starting growth hormone, the blood levels of CNP and NTproCNP start to increase.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2010-11 |
| Est. Completion | 2014-09 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01504802
The ClinicalTrials.gov registry entry for NCT01504802 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 22 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Nemours Children's Clinic, which has 108 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT01504802 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01504802 about?
NCT01504802 is a clinical study titled "Pharmacodynamics of CNP During Growth Hormone Treatment". It is now widespread practice to treat children with short stature with growth hormone. However, how an individual child will respond to growth hormone treatment is unpredictable and highly variable. Some children will not respond to growth hormone treatment at all. Currently, the only way to determ...
What is the current status of trial NCT01504802?
This trial is currently completed. The enrollment target is 22 participants. The study started on 2010-11. Estimated completion is 2014-09.
Who is sponsoring clinical trial NCT01504802?
This trial is sponsored by Nemours Children's Clinic, which has 108 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.