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NCT01499277 · ClinicalTrials.gov registry record · Phase 3

Evaluation of Ceftaroline Fosamil Versus Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections

A Phase 3 study, sponsored by Pfizer.

Completed
Registry status
Phase 3
Development phase
802
Enrollment target

NCT01499277: Completed Phase 3 study, sponsored by Pfizer.

NCT01499277 is a Phase 3 study that has completed, run by Pfizer. The registered enrollment target is 802 participants, roughly in line with the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01499277, a Phase 3 study, has completed, sponsored by Pfizer.

COMPLETED
Registry status
Phase 3
Development phase
802 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the effects of Ceftaroline Fosamil versus Vancomycin plus Aztreonam in treatment of patients with complicated bacterial skin and soft tissue infections.

Primary Outcome

The observed difference in the clinical cure rates at TOC (ceftaroline group minus vancomycin plus aztreonam group) in MITT. Clinical cure rate is measured by comparing the participant's signs and symptoms at TOC visit to those recorded at study baseline.

Interventions

  • DRUG Vancomycin
  • DRUG Ceftaroline fosamil
  • DRUG Aztreonam

Trial Details

FieldValue
Enrollment Target 802 participants
Start Date 2012-05
Est. Completion 2015-01
Phase Phase 3
Pfizer

1,845 total trials

What the finished NCT01499277 record still lists

NCT01499277 is an interventional study that assigns participants to a tested intervention. The registered 802 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target.

The record links to 0 conditions, and to 3 interventions - of which Vancomycin is the first listed.

NCT01499277 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01499277 about?

NCT01499277 is a clinical study titled "Evaluation of Ceftaroline Fosamil Versus Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections". The purpose of this study is to evaluate the effects of Ceftaroline Fosamil versus Vancomycin plus Aztreonam in treatment of patients with complicated bacterial skin and soft tissue infections.

What is the current status of trial NCT01499277?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 802 participants. The study started on 2012-05. Estimated completion is 2015-01.

What interventions are being tested in trial NCT01499277?

The interventions under investigation include: Vancomycin (DRUG), Ceftaroline fosamil (DRUG), Aztreonam (DRUG).

Who is sponsoring clinical trial NCT01499277?

This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01499277's enrollment target sits among peer trials

802 413th of 2000 higher than 1,587 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01499277, the US trial registry maintained by the National Library of Medicine. NCT01499277 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.