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NCT01496495 · ClinicalTrials.gov registry record · Phase 1

A Study of ARRY-614 in Patients With Low or Intermediate-1 Risk Myelodysplastic Syndromes

A Phase 1 study, sponsored by Array Biopharma, now a wholly owned subsidiary of Pfizer.

Completed
Registry status
Phase 1
Development phase
71
Enrollment target

NCT01496495 is a Phase 1 study that has completed, run by Array Biopharma, now a wholly owned subsidiary of Pfizer. The registered enrollment target is 71 participants.

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The verdict

NCT01496495, a Phase 1 study, has completed, sponsored by Array Biopharma, now a wholly owned subsidiary of Pfizer.

COMPLETED
Registry status
Phase 1
Development phase
71 participants
Enrollment target

Study Summary

This is a Phase 1 study during which patients with low or intermediate-1 risk myelodysplastic syndromes (MDS) will receive investigational study drug ARRY-614. This study has 2 parts. In the first part, patients will receive increasing doses of study drug in order to achieve the highest dose of the study drug possible that will not cause unacceptable side effects. Approximately 50 patients from the US will be enrolled in Part 1 (Completed). In the second part of the study, patients will receive the best dose of study drug determined from the first part of the study and will be followed to see what side effects and effectiveness the study drug has, if any, in treating the cancer. Approximately 30 patients from the US will be enrolled in Part 2 (Completed).

Interventions

  • DRUG ARRY-614, p38/Tie2 inhibitor; oral

Trial Details

FieldValue
Enrollment Target 71 participants
Start Date 2012-01
Est. Completion 2015-03-18
Phase Phase 1

What the Registry Record Tells You About NCT01496495

The ClinicalTrials.gov registry entry for NCT01496495 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 71 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Array Biopharma, now a wholly owned subsidiary of Pfizer, which has 21 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which ARRY-614, p38/Tie2 inhibitor; oral is the first listed.

NCT01496495 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01496495 about?

NCT01496495 is a clinical study titled "A Study of ARRY-614 in Patients With Low or Intermediate-1 Risk Myelodysplastic Syndromes". This is a Phase 1 study during which patients with low or intermediate-1 risk myelodysplastic syndromes (MDS) will receive investigational study drug ARRY-614. This study has 2 parts. In the first part, patients will receive increasing doses of study drug in order to achieve the highest dose of the...

What is the current status of trial NCT01496495?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 71 participants. The study started on 2012-01. Estimated completion is 2015-03-18.

What interventions are being tested in trial NCT01496495?

The interventions under investigation include: ARRY-614, p38/Tie2 inhibitor; oral (DRUG).

Who is sponsoring clinical trial NCT01496495?

This trial is sponsored by Array Biopharma, now a wholly owned subsidiary of Pfizer, which has 21 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.