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NCT01489059 · ClinicalTrials.gov registry record · Phase 1
Safety Study of IL-21/Ipilimumab Combination in the Treatment of Melanoma
A Phase 1 study, sponsored by Bristol-Myers Squibb.
- Completed
- Registry status
- Phase 1
- Development phase
- 42
- Enrollment target
NCT01489059: Completed Phase 1 study, sponsored by Bristol-Myers Squibb.
NCT01489059 is a Phase 1 study that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 42 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (30% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01489059, a Phase 1 study, has completed, sponsored by Bristol-Myers Squibb.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 42 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether the combination of interleukin-21 (IL-21) and Ipilimumab in subjects with melanoma is safe, and provide preliminary information on the clinical benefits of the combination compared with Ipilimumab alone
Primary Outcome
Based on the dose-limiting toxicity (DLT) rate
Interventions
- BIOLOGICAL Ipilimumab
- BIOLOGICAL BMS-982470 (recombinant interleukin-21)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2011-12 |
| Est. Completion | 2014-06 |
| Phase | Phase 1 |
What the finished NCT01489059 record still lists
NCT01489059 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 42 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (30% lower).
The record links to 0 conditions, and to 2 interventions - of which Ipilimumab is the first listed.
NCT01489059 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01489059 about?
NCT01489059 is a clinical study titled "Safety Study of IL-21/Ipilimumab Combination in the Treatment of Melanoma". The purpose of this study is to determine whether the combination of interleukin-21 (IL-21) and Ipilimumab in subjects with melanoma is safe, and provide preliminary information on the clinical benefits of the combination compared with Ipilimumab alone
What is the current status of trial NCT01489059?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 42 participants. The study started on 2011-12. Estimated completion is 2014-06.
What interventions are being tested in trial NCT01489059?
The interventions under investigation include: Ipilimumab (BIOLOGICAL), BMS-982470 (recombinant interleukin-21) (BIOLOGICAL).
Who is sponsoring clinical trial NCT01489059?
This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01489059's enrollment target sits among peer trials
42 1105th of 2000 higher than 876 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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