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NCT01482351 · ClinicalTrials.gov registry record · NA
Mild Cognitive Impairment and Obstructive Sleep Apnea
A NA study, sponsored by George Mason University.
- Completed
- Registry status
- NA
- Development phase
- 54
- Enrollment target
NCT01482351: Completed NA study, sponsored by George Mason University.
NCT01482351 is a NA study that has completed, run by George Mason University. The registered enrollment target is 54 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01482351, a NA study, has completed, sponsored by George Mason University.
- COMPLETED
- Registry status
- NA
- Development phase
- 54 participants
- Enrollment target
Study Summary
Obstructive sleep apnea (OSA) has been linked to increased risk for Alzheimer's disease (AD), but little prospective evidence exists on the effects of OSA treatment in preclinical AD. The objective was to determine if CPAP treatment adherence, controlling for baseline differences, predicts cognitive and everyday function after 1 year in older adults with MCI and to determine effect sizes for a larger trial. The aim of the Mild Cognitive Impairment and Obstructive Sleep Apnea (Memories 1) trial was to determine whether CPAP treatment adherence, controlling for any baseline differences in OSA severity, ApoE4, and other previously identified demographic and patient factors, might predict cognitive and everyday function after 1 year in older adults with amnestic MCI.
Primary Outcome
Memory (immediate and delayed recall) will be assessed using HVLT-R. HVLT-R has been used in elders with Alzheimer's Disease and takes 10 minutes to complete. Total score ranges from 0 to 60, a higher score indicates a better memory (better outcome).
Interventions
- BEHAVIORAL CPAP adherence intervention
- BEHAVIORAL Attention control intervention
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 54 participants |
| Start Date | 2012-09 |
| Est. Completion | 2014-12 |
| Phase | NA |
What the finished NCT01482351 record still lists
NCT01482351 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 54 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which CPAP adherence intervention is the first listed.
NCT01482351 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01482351 about?
NCT01482351 is a clinical study titled "Mild Cognitive Impairment and Obstructive Sleep Apnea". Obstructive sleep apnea (OSA) has been linked to increased risk for Alzheimer's disease (AD), but little prospective evidence exists on the effects of OSA treatment in preclinical AD. The objective was to determine if CPAP treatment adherence, controlling for baseline differences, predicts cognitive...
What is the current status of trial NCT01482351?
This trial is currently completed. It is a NA study. The enrollment target is 54 participants. The study started on 2012-09. Estimated completion is 2014-12.
What interventions are being tested in trial NCT01482351?
The interventions under investigation include: CPAP adherence intervention (BEHAVIORAL), Attention control intervention (BEHAVIORAL).
Who is sponsoring clinical trial NCT01482351?
This trial is sponsored by George Mason University, which has 25 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01482351's enrollment target sits among peer trials
54 1268th of 2000 higher than 730 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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