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NCT01477463 · ClinicalTrials.gov registry record · NA
Pilot Trial to Evaluate the Effect of Vitamin D on Melanocyte Biomarkers
A NA study, sponsored by Stanford University.
- Completed
- Registry status
- NA
- Development phase
- 24
- Enrollment target
NCT01477463: Completed NA study, sponsored by Stanford University.
NCT01477463 is a NA study that has completed, run by Stanford University. The registered enrollment target is 24 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01477463, a NA study, has completed, sponsored by Stanford University.
- COMPLETED
- Registry status
- NA
- Development phase
- 24 participants
- Enrollment target
Study Summary
The purpose of this study is to determine the signaling pathways and changes in gene expression in melanocytes of subjects with a history of non-melanoma skin cancer who are exposed to oral vitamin D. If vitamin D is found to inhibit a signaling pathway involved in the development of melanoma such as BRAF, a protein involved in cell proliferation, then oral vitamin D could be explored further as a chemoprevention for melanoma skin cancer.
Primary Outcome
Normal cells have a complex series of molecular signals that allow communication between cells and to the cell nucleus. These signals work together to control one or more cell functions, such as cell division or cell death. Abnormal signaling activity caused by changes in gene expression can lead to cancer. An understanding of abnormal signaling, both in the tumor and in normal tissues, may lead to new therapies in cancer patients. We wish to identify changes in molecular signaling that occur in
Interventions
- DRUG Vitamin D3
- DRUG placebo and vitamin D
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2012-09 |
| Est. Completion | 2014-05 |
| Phase | NA |
What the finished NCT01477463 record still lists
NCT01477463 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Vitamin D3 is the first listed.
NCT01477463 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01477463 about?
NCT01477463 is a clinical study titled "Pilot Trial to Evaluate the Effect of Vitamin D on Melanocyte Biomarkers". The purpose of this study is to determine the signaling pathways and changes in gene expression in melanocytes of subjects with a history of non-melanoma skin cancer who are exposed to oral vitamin D. If vitamin D is found to inhibit a signaling pathway involved in the development of melanoma such a...
What is the current status of trial NCT01477463?
This trial is currently completed. It is a NA study. The enrollment target is 24 participants. The study started on 2012-09. Estimated completion is 2014-05.
What interventions are being tested in trial NCT01477463?
The interventions under investigation include: Vitamin D3 (DRUG), placebo and vitamin D (DRUG).
Who is sponsoring clinical trial NCT01477463?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01477463's enrollment target sits among peer trials
24 1736th of 2000 higher than 246 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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