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NCT01469585 · ClinicalTrials.gov registry record · NA
Oral Contraceptives and Subantimicrobial Doxycycline: Effect on Endometrial Matrix Metalloproteinases
A NA study of Breakthrough Bleeding, sponsored by University of Hawaii.
- Completed
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT01469585: Completed NA study of Breakthrough Bleeding, sponsored by University of Hawaii.
NCT01469585 is a NA study of Breakthrough Bleeding that has completed, run by University of Hawaii. The registered enrollment target is 20 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01469585, a NA study of Breakthrough Bleeding, has completed, sponsored by University of Hawaii.
- COMPLETED
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to compare the effects (good and bad) of subantimicrobial dose doxycycline on the irregular bleeding women experience when taking continuous oral contraceptive pills. This research is being done because currently, there is no effective treatment for this condition. Findings from this study could help to decrease the side effects of birth control pills and decrease unplanned pregnancies.
Primary Outcome
Baseline Matrix Metalloproteinase expression (activity level) will be determined on day 19-21 of cycle 1. During cycle 2, when women are taking the cyclic oral contraceptive, the endometrial biopsy will be performed between cycle day 19-21 (study day 47-49), prior to endometrial degradation and activity level will be noted. Of note, the outcome is MMP activity level, not a change in level.
Conditions Studied
Interventions
- DRUG Doxycycline
Study Locations (1)
Hawaii
- Kapiolani Medical Center for Women and Children - Honolulu
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2011-11 |
| Est. Completion | 2012-05 |
| Phase | NA |
What the finished NCT01469585 record still lists
NCT01469585 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Breakthrough Bleeding appearing as the primary indexed condition, and to 1 intervention - of which Doxycycline is the first listed.
NCT01469585 reports a single indexed study location in Hawaii.
Frequently Asked Questions
What is clinical trial NCT01469585 about?
NCT01469585 is a clinical study titled "Oral Contraceptives and Subantimicrobial Doxycycline: Effect on Endometrial Matrix Metalloproteinases". The purpose of this study is to compare the effects (good and bad) of subantimicrobial dose doxycycline on the irregular bleeding women experience when taking continuous oral contraceptive pills. This research is being done because currently, there is no effective treatment for this condition. Findi...
What is the current status of trial NCT01469585?
This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2011-11. Estimated completion is 2012-05.
What conditions does trial NCT01469585 study?
This clinical trial studies the following conditions: Breakthrough Bleeding.
What interventions are being tested in trial NCT01469585?
The interventions under investigation include: Doxycycline (DRUG).
Who is sponsoring clinical trial NCT01469585?
This trial is sponsored by University of Hawaii, which has 77 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01469585 being conducted?
This trial has 1 study location across Hawaii. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breakthrough Bleeding
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01469585's enrollment target sits among peer trials
20 1768th of 2000 higher than 140 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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