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NCT01462448 · ClinicalTrials.gov registry record
Study to Identify the Genetic Variations Associated With Phantom Limb Pain
A clinical trial, sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine.
- Completed
- Registry status
- 726
- Enrollment target
NCT01462448: Completed study, sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine.
NCT01462448 is a clinical trial that has completed, run by Henry M. Jackson Foundation for the Advancement of Military Medicine. The registered enrollment target is 726 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01462448 has completed, sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine.
- COMPLETED
- Registry status
- 726 participants
- Enrollment target
Study Summary
The purpose of this study is to determine if there is a genetic component to phantom limb pain. DNA will be analyzed for single nucleotide polymorphisms (SNPs) between the control and phantom limb pain group. Total RNA will also be isolated and profiled to asses the degree to which our gene(s) of interest are expressed in the presence or absence of phantom limb pain. Some proteins, such as inflammatory antibodies or the neurotrophin brain-derived neurotrophic factor (BDNF), will also be assessed for their association(s) with phantom limb pain.
Primary Outcome
The primary outcome measure for this study is the identification of unique SNPs that may correlate with PLP. Patients will undergo a one-time blood draw and fill out a survey characterizing their phantom limb pain. The PLP characteristics along with DNA analysis using Affymetrix SNP chip technology will be used to match genotype with phenotype.
Interventions
- PROCEDURE Blood Draw
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 726 participants |
| Start Date | 2012-03 |
| Est. Completion | 2023-08-06 |
What the finished NCT01462448 record still lists
NCT01462448 is an observational study that tracks outcomes without assigning an intervention. The registered 726 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 1 intervention - of which Blood Draw is the first listed.
NCT01462448 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01462448 about?
NCT01462448 is a clinical study titled "Study to Identify the Genetic Variations Associated With Phantom Limb Pain". The purpose of this study is to determine if there is a genetic component to phantom limb pain. DNA will be analyzed for single nucleotide polymorphisms (SNPs) between the control and phantom limb pain group. Total RNA will also be isolated and profiled to asses the degree to which our gene(s) of in...
What is the current status of trial NCT01462448?
This trial is currently completed. The enrollment target is 726 participants. The study started on 2012-03. Estimated completion is 2023-08-06.
What interventions are being tested in trial NCT01462448?
The interventions under investigation include: Blood Draw (PROCEDURE).
Who is sponsoring clinical trial NCT01462448?
This trial is sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine, which has 60 total clinical trials registered on ClinicalTrials.gov.
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