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NCT01457677 · ClinicalTrials.gov registry record · Phase 2
ARTDeCo Study: A Study of RO4995819 in Patients With Major Depressive Disorder And Inadequate Response to Ongoing Antidepressant Treatment
A Phase 2 study, sponsored by Hoffmann-La Roche.
- Completed
- Registry status
- Phase 2
- Development phase
- 357
- Enrollment target
NCT01457677: Completed Phase 2 study, sponsored by Hoffmann-La Roche.
NCT01457677 is a Phase 2 study that has completed, run by Hoffmann-La Roche. The registered enrollment target is 357 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (168% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01457677, a Phase 2 study, has completed, sponsored by Hoffmann-La Roche.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 357 participants
- Enrollment target
Study Summary
This multi-center, randomized, double-blind, placebo-controlled, parallel-group study will investigate the efficacy and safety of RO4995819 as adjunctive therapy in patients with major depressive disorder having inadequate response to ongoing antidepressant treatment. Patients will be randomized to receive once daily doses of 5 mg, 15 or 30 mg of RO4995819 or matching placebo. The anticipated time on study treatment is 6 weeks.
Interventions
- DRUG Placebo
- DRUG RO4995819
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 357 participants |
| Start Date | 2011-12 |
| Est. Completion | 2014-06 |
| Phase | Phase 2 |
What the finished NCT01457677 record still lists
NCT01457677 is an interventional study that assigns participants to a tested intervention. The registered 357 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (168% higher).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT01457677 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01457677 about?
NCT01457677 is a clinical study titled "ARTDeCo Study: A Study of RO4995819 in Patients With Major Depressive Disorder And Inadequate Response to Ongoing Antidepressant Treatment". This multi-center, randomized, double-blind, placebo-controlled, parallel-group study will investigate the efficacy and safety of RO4995819 as adjunctive therapy in patients with major depressive disorder having inadequate response to ongoing antidepressant treatment. Patients will be randomized to ...
What is the current status of trial NCT01457677?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 357 participants. The study started on 2011-12. Estimated completion is 2014-06.
What interventions are being tested in trial NCT01457677?
The interventions under investigation include: Placebo (DRUG), RO4995819 (DRUG).
Who is sponsoring clinical trial NCT01457677?
This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01457677's enrollment target sits among peer trials
357 127th of 2000 higher than 1,873 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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