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NCT01454141 · ClinicalTrials.gov registry record · NA
Cognitive Control Training for Depression
A NA study, sponsored by Boston University.
- Completed
- Registry status
- NA
- Development phase
- 56
- Enrollment target
NCT01454141 is a NA study that has completed, run by Boston University. The registered enrollment target is 56 participants.
The verdict
NCT01454141, a NA study, has completed, sponsored by Boston University.
- COMPLETED
- Registry status
- NA
- Development phase
- 56 participants
- Enrollment target
Study Summary
Depression is frequently characterized by patterns of inflexible, maladaptive, and ruminative thinking styles; these patterns themselves are thought to result from a combination of decreased attentional control, decreased executive functioning, and increased negative affect. Specifically, the dorsolateral prefrontal cortex has been hypothesized to play a central role in emotion regulation by recruiting resources necessary for executive control. Recent advances have been made in neurobehavioral training strategies as interventions for emotional disorders such as depression. Cognitive control training (CCT) uses computer-based exercises to recruit and activate prefrontal neural networks via repeated behavioral exercises, with the aim of strengthening cognitive and emotional functions. A previous study found that severely depressed participants who received CCT exhibited reduced negative affect and rumination as well as improved focus and concentration. The present study aimed to extend this line of research by employing a more stringent control group and testing the efficacy of three sessions of CCT over a two-week period in a community population with depressed mood. Forty-eight participants with high BDI-II scores were randomized to CCT or a comparison condition (Peripheral Vision Training; PVT). The investigators hypothesized that relative to a control condition (PVT), CCT would be associated with less self-reported negative mood and emotional reactivity.
Interventions
- OTHER Cognitive Control Training
- OTHER Peripheral Vision Task
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2010-07 |
| Est. Completion | 2011-06 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01454141
The ClinicalTrials.gov registry entry for NCT01454141 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 56 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Boston University, which has 185 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Cognitive Control Training is the first listed.
NCT01454141 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01454141 about?
NCT01454141 is a clinical study titled "Cognitive Control Training for Depression". Depression is frequently characterized by patterns of inflexible, maladaptive, and ruminative thinking styles; these patterns themselves are thought to result from a combination of decreased attentional control, decreased executive functioning, and increased negative affect. Specifically, the dorsol...
What is the current status of trial NCT01454141?
This trial is currently completed. It is a NA study. The enrollment target is 56 participants. The study started on 2010-07. Estimated completion is 2011-06.
What interventions are being tested in trial NCT01454141?
The interventions under investigation include: Cognitive Control Training (OTHER), Peripheral Vision Task (OTHER).
Who is sponsoring clinical trial NCT01454141?
This trial is sponsored by Boston University, which has 185 total clinical trials registered on ClinicalTrials.gov.
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