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NCT01452035 · ClinicalTrials.gov registry record · NA
Exercise Dose Response for Improving Insulin Sensitivity
A NA study, sponsored by University of Michigan.
- Completed
- Registry status
- NA
- Development phase
- 13
- Enrollment target
NCT01452035: Completed NA study, sponsored by University of Michigan.
NCT01452035 is a NA study that has completed, run by University of Michigan. The registered enrollment target is 13 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01452035, a NA study, has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- NA
- Development phase
- 13 participants
- Enrollment target
Study Summary
Many of the beneficial metabolic effects of endurance exercise training are not due to adaptations to weeks, months, or even years of training, but rather much is due to the response to the most recent exercise session(s). Therefore, the investigators contend that lifestyle interventions for obese individuals should be tailored to optimize the metabolic effects of the most recent exercise session(s). But the "dose" of exercise necessary to evoke these beneficial responses is not known, and the mechanisms responsible for these improvements are poorly understood. The findings from these studies will: 1) establish the minimum "dose" of a single exercise session necessary to improve insulin sensitivity the next day in obese adults, 2) characterize the underlying metabolic factors responsible for the improvement in insulin sensitivity, and 3) assess the cumulative metabolic adaptations that occur over days, weeks, and months of a low-intensity/low-volume lifestyle exercise program. Findings from these studies will provide valuable information for the development of lifestyle programs aimed at maximizing the key metabolic health benefits of each exercise session in obese patients.
Primary Outcome
A hyperinsulinemic-euglycemic clamp will be used to assess peripheral insulin sensitivity and will be performed using a primed 2h insulin infusion at a rate of 100 mU/m2/min.
Interventions
- OTHER Exercise
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 13 participants |
| Start Date | 2009-01 |
| Est. Completion | 2015-12 |
| Phase | NA |
What the finished NCT01452035 record still lists
NCT01452035 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Exercise is the first listed.
NCT01452035 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01452035 about?
NCT01452035 is a clinical study titled "Exercise Dose Response for Improving Insulin Sensitivity". Many of the beneficial metabolic effects of endurance exercise training are not due to adaptations to weeks, months, or even years of training, but rather much is due to the response to the most recent exercise session(s). Therefore, the investigators contend that lifestyle interventions for obese i...
What is the current status of trial NCT01452035?
This trial is currently completed. It is a NA study. The enrollment target is 13 participants. The study started on 2009-01. Estimated completion is 2015-12.
What interventions are being tested in trial NCT01452035?
The interventions under investigation include: Exercise (OTHER).
Who is sponsoring clinical trial NCT01452035?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01452035's enrollment target sits among peer trials
13 1911th of 2000 higher than 88 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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