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NCT01451970 · ClinicalTrials.gov registry record · NA
Dietary Fatty Acid Composition and Obesity-related Metabolic Abnormalities
A NA study of Overweight/Obese Women, sponsored by University of Michigan.
- Completed
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT01451970 is a NA study of Overweight/Obese Women that has completed, run by University of Michigan. The registered enrollment target is 40 participants. The trial reports 1 study location across 1 state.
The verdict
NCT01451970, a NA study of Overweight/Obese Women, has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
Individuals have a significant capacity to adapt to different environments by changing their core metabolic pathways. This adaptation is especially important in regards to diet. Epidemiological research over the last several decades have shown that diets high in saturated fats have a greater ability to cause insulin resistance and the 'metabolic syndrome' while diets low in saturated fats (or a so called 'Mediterranean Diet), reduces the risk for cardiovascular disease. In humans, experimental diets high in unsaturated fats, as compared to high carbohydrate or high saturated fat diets, result in increased insulin sensitivity and improved lipid profiles. In this application, the investigators propose to systematically assess the effects of two diets enriched in either saturated or unsaturated fatty acids and determine the cellular and molecular mechanisms of the apparent increase in insulin sensitivity. The investigators hypothesize that individuals will 'adapt' to the different diets and the investigators will be able to generate predictive alterations in gene expression and metabolites that underlie the alterations in metabolism. In parallel, the investigators will test the ability of these different diets to affect the release of gastrointestinal hormones that may be critical to modulation of appetite.
Conditions Studied
Interventions
- OTHER High Fat Diet
Study Locations (1)
Michigan
- Michigan Clincal Research Unit - Ann Arbor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2007-08 |
| Est. Completion | 2010-12-12 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01451970
The ClinicalTrials.gov registry entry for NCT01451970 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Michigan, which has 1,327 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Overweight/Obese Women appearing as the primary indexed condition, and to 1 intervention - of which High Fat Diet is the first listed.
NCT01451970 reports 1 study location spanning 1 distinct geographic area - top geographies include Michigan.
Frequently Asked Questions
What is clinical trial NCT01451970 about?
NCT01451970 is a clinical study titled "Dietary Fatty Acid Composition and Obesity-related Metabolic Abnormalities". Individuals have a significant capacity to adapt to different environments by changing their core metabolic pathways. This adaptation is especially important in regards to diet. Epidemiological research over the last several decades have shown that diets high in saturated fats have a greater ability...
What is the current status of trial NCT01451970?
This trial is currently completed. It is a NA study. The enrollment target is 40 participants. The study started on 2007-08. Estimated completion is 2010-12-12.
What conditions does trial NCT01451970 study?
This clinical trial studies the following conditions: Overweight/Obese Women.
What interventions are being tested in trial NCT01451970?
The interventions under investigation include: High Fat Diet (OTHER).
Who is sponsoring clinical trial NCT01451970?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01451970 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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