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NCT01450852 · ClinicalTrials.gov registry record · NA
Strength Training Induced Alterations in Markers of Immune Function
A NA study, sponsored by Louisiana State University Health Sciences Center in New Orleans.
- Completed
- Registry status
- NA
- Development phase
- 42
- Enrollment target
NCT01450852 is a NA study that has completed, run by Louisiana State University Health Sciences Center in New Orleans. The registered enrollment target is 42 participants.
The verdict
NCT01450852, a NA study, has completed, sponsored by Louisiana State University Health Sciences Center in New Orleans.
- COMPLETED
- Registry status
- NA
- Development phase
- 42 participants
- Enrollment target
Study Summary
Exercise has been used to help prevent or slow the progression of inflammation-related disease; however, the mechanism by which this activity may lower concentrations of inflammatory markers remains unclear. The melanocortin receptors 1,3 and 5 (MC1R, MC3R and MC5R) have been shown to function in an anti-inflammatory manner and have the potential to mediate the positive immune adaptations associated with regular physical activity. Preliminary data suggest that MC3R gene expression increases in whole blood after chronic exercise training. The primary aim of the current study is to explore whether this change in gene expression translates into alterations in MC1R, MC3R, or MC5R monocyte surface expression. The secondary aim is to examine the relationship between surface expression of these receptors and circulating inflammatory profiles. The investigators will recruit 42 untrained, healthy males and females aged 18-35 yrs. Half of the group will be placed on an exercise program for 15 weeks. The other half will serve as untrained control subjects. In addition to basic anthropometric measures, the investigators will measure concentrations of inflammatory and anti-inflammatory cytokines (ELISA) and cell surface expression of MC1R, MC3R, and MC5R on monocytes (flow cytometry).
Interventions
- BEHAVIORAL Strength Training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2010-01 |
| Est. Completion | 2010-05 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01450852
The ClinicalTrials.gov registry entry for NCT01450852 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 42 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Louisiana State University Health Sciences Center in New Orleans, which has 45 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Strength Training is the first listed.
NCT01450852 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01450852 about?
NCT01450852 is a clinical study titled "Strength Training Induced Alterations in Markers of Immune Function". Exercise has been used to help prevent or slow the progression of inflammation-related disease; however, the mechanism by which this activity may lower concentrations of inflammatory markers remains unclear. The melanocortin receptors 1,3 and 5 (MC1R, MC3R and MC5R) have been shown to function in an...
What is the current status of trial NCT01450852?
This trial is currently completed. It is a NA study. The enrollment target is 42 participants. The study started on 2010-01. Estimated completion is 2010-05.
What interventions are being tested in trial NCT01450852?
The interventions under investigation include: Strength Training (BEHAVIORAL).
Who is sponsoring clinical trial NCT01450852?
This trial is sponsored by Louisiana State University Health Sciences Center in New Orleans, which has 45 total clinical trials registered on ClinicalTrials.gov.
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