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NCT01447225 · ClinicalTrials.gov registry record · Phase 1
Safety Study of MM-121 in Combination With Multiple Anticancer Therapies in Patients With Advanced Solid Tumors
A Phase 1 study, sponsored by Merrimack Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 43
- Enrollment target
NCT01447225: Completed Phase 1 study, sponsored by Merrimack Pharmaceuticals.
NCT01447225 is a Phase 1 study that has completed, run by Merrimack Pharmaceuticals. The registered enrollment target is 43 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (28% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01447225, a Phase 1 study, has completed, sponsored by Merrimack Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 43 participants
- Enrollment target
Study Summary
To evaluate the safety and tolerability of escalating doses of MM-121 + certain anticancer therapies
Primary Outcome
Safety and tolerability data presented in detail in the adverse events and serious adverse events section of the results posting
Interventions
- DRUG Carboplatin
- DRUG Pemetrexed
- DRUG Gemcitabine
- DRUG Cabazitaxel
- DRUG MM-121
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 43 participants |
| Start Date | 2011-10 |
| Est. Completion | 2014-01 |
| Phase | Phase 1 |
What the finished NCT01447225 record still lists
NCT01447225 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 43 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (28% lower).
The record links to 0 conditions, and to 5 interventions - of which Carboplatin is the first listed.
NCT01447225 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01447225 about?
NCT01447225 is a clinical study titled "Safety Study of MM-121 in Combination With Multiple Anticancer Therapies in Patients With Advanced Solid Tumors". To evaluate the safety and tolerability of escalating doses of MM-121 + certain anticancer therapies
What is the current status of trial NCT01447225?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 43 participants. The study started on 2011-10. Estimated completion is 2014-01.
What interventions are being tested in trial NCT01447225?
The interventions under investigation include: Carboplatin (DRUG), Pemetrexed (DRUG), Gemcitabine (DRUG), Cabazitaxel (DRUG), MM-121 (DRUG).
Who is sponsoring clinical trial NCT01447225?
This trial is sponsored by Merrimack Pharmaceuticals, which has 22 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01447225's enrollment target sits among peer trials
43 1100th of 2000 higher than 896 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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