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NCT01445028 · ClinicalTrials.gov registry record · Phase 4
Isotretinoin for Proliferative Vitreoretinopathy
A Phase 4 study, sponsored by Wills Eye.
- Completed
- Registry status
- Phase 4
- Development phase
- 109
- Enrollment target
NCT01445028: Completed Phase 4 study, sponsored by Wills Eye.
NCT01445028 is a Phase 4 study that has completed, run by Wills Eye. The registered enrollment target is 109 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (79% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01445028, a Phase 4 study, has completed, sponsored by Wills Eye.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 109 participants
- Enrollment target
Study Summary
Proliferative vitreoretinopathy (PVR), or secondary scarring on and around the retina, is an important cause of retinal re-detachment. The purpose of this study is to evaluate the effect of oral isotretinoin, which inhibits the growth of cells responsible for proliferative vitreoretinopathy (PVR), on recurrent retinal detachment.
Primary Outcome
We will evaluate all patients for retinal attachment at 3 months.
Interventions
- DRUG Isotretinoin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 109 participants |
| Start Date | 2011-09 |
| Est. Completion | 2015-08 |
| Phase | Phase 4 |
What the finished NCT01445028 record still lists
NCT01445028 is an interventional study that assigns participants to a tested intervention. The registered 109 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (79% lower).
The record links to 0 conditions, and to 1 intervention - of which Isotretinoin is the first listed.
NCT01445028 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01445028 about?
NCT01445028 is a clinical study titled "Isotretinoin for Proliferative Vitreoretinopathy". Proliferative vitreoretinopathy (PVR), or secondary scarring on and around the retina, is an important cause of retinal re-detachment. The purpose of this study is to evaluate the effect of oral isotretinoin, which inhibits the growth of cells responsible for proliferative vitreoretinopathy (PVR), o...
What is the current status of trial NCT01445028?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 109 participants. The study started on 2011-09. Estimated completion is 2015-08.
What interventions are being tested in trial NCT01445028?
The interventions under investigation include: Isotretinoin (DRUG).
Who is sponsoring clinical trial NCT01445028?
This trial is sponsored by Wills Eye, which has 59 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01445028's enrollment target sits among peer trials
109 737th of 2000 higher than 1,261 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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