Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01437319 · ClinicalTrials.gov registry record · Phase 1
Mucin Balls and Corneal Inflammation Events
A Phase 1 study, sponsored by Johnson & Johnson Vision Care.
- Completed
- Registry status
- Phase 1
- Development phase
- 289
- Enrollment target
NCT01437319: Completed Phase 1 study, sponsored by Johnson & Johnson Vision Care.
NCT01437319 is a Phase 1 study that has completed, run by Johnson & Johnson Vision Care. The registered enrollment target is 289 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (382% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01437319, a Phase 1 study, has completed, sponsored by Johnson & Johnson Vision Care.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 289 participants
- Enrollment target
Study Summary
The purpose of this study is to determine if the formation of mucin balls is a marker for protection from inflammatory events to the cornea and if mucin balls play a role in protection during extended contact lens wear.
Primary Outcome
The percentage of Subjects that experienced Corneal Inflammatory Events within their Mucin Ball classification.
Interventions
- DEVICE comfilcon A
- DEVICE balafilcon A
- DEVICE lotrafilcon A
- OTHER etafilcon A
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 289 participants |
| Start Date | 2011-09 |
| Est. Completion | 2014-02 |
| Phase | Phase 1 |
What the finished NCT01437319 record still lists
NCT01437319 is an interventional study that assigns participants to a tested intervention. The registered 289 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (382% higher).
The record links to 0 conditions, and to 4 interventions - of which comfilcon A is the first listed.
NCT01437319 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01437319 about?
NCT01437319 is a clinical study titled "Mucin Balls and Corneal Inflammation Events". The purpose of this study is to determine if the formation of mucin balls is a marker for protection from inflammatory events to the cornea and if mucin balls play a role in protection during extended contact lens wear.
What is the current status of trial NCT01437319?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 289 participants. The study started on 2011-09. Estimated completion is 2014-02.
What interventions are being tested in trial NCT01437319?
The interventions under investigation include: comfilcon A (DEVICE), balafilcon A (DEVICE), lotrafilcon A (DEVICE), etafilcon A (OTHER).
Who is sponsoring clinical trial NCT01437319?
This trial is sponsored by Johnson & Johnson Vision Care, which has 142 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01437319's enrollment target sits among peer trials
289 139th of 2000 higher than 1,862 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT06465199 · 289 participants · Phase 1
Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas
- NCT00775476 · 290 participants · Phase 2
Treatment of Systemic Lupus Erythematosus (SLE) With N-acetylcysteine
- NCT01874197 · 290 participants · NA
Branched Thoracic Endovascular Grafts for the Treatment of Thoraco-abdominal Aortic
- NCT04331353 · 290 participants · NA
The Allergen Reduction and Child Health Study (ARCHS)
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia