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NCT01433913 · ClinicalTrials.gov registry record · Phase 2
Metformin Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery
A Phase 2 study, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- Phase 2
- Development phase
- 20
- Enrollment target
NCT01433913: Completed Phase 2 study, sponsored by National Cancer Institute (NCI).
NCT01433913 is a Phase 2 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 20 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01433913, a Phase 2 study, has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 20 participants
- Enrollment target
Study Summary
This randomized phase II trial studies how well metformin hydrochloride works compared to placebo in treating patients with prostate cancer undergoing surgery. Metformin hydrochloride may make some enzymes active. These enzymes may block other enzymes needed for cell growth and stop the growth of tumor cells.
Primary Outcome
Data between the two study groups will be compared using a two-group t-test at a two-sided 0.05 level of significance. If the data are not normally distributed, a non-parametric rank-sum test will be utilized.
Interventions
- OTHER laboratory biomarker analysis
- OTHER placebo
- DRUG metformin hydrochloride
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2011-11 |
| Est. Completion | 2014-04 |
| Phase | Phase 2 |
What the finished NCT01433913 record still lists
NCT01433913 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower).
The record links to 0 conditions, and to 3 interventions - of which laboratory biomarker analysis is the first listed.
NCT01433913 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01433913 about?
NCT01433913 is a clinical study titled "Metformin Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery". This randomized phase II trial studies how well metformin hydrochloride works compared to placebo in treating patients with prostate cancer undergoing surgery. Metformin hydrochloride may make some enzymes active. These enzymes may block other enzymes needed for cell growth and stop the growth of tu...
What is the current status of trial NCT01433913?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2011-11. Estimated completion is 2014-04.
What interventions are being tested in trial NCT01433913?
The interventions under investigation include: laboratory biomarker analysis (OTHER), placebo (OTHER), metformin hydrochloride (DRUG).
Who is sponsoring clinical trial NCT01433913?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01433913's enrollment target sits among peer trials
20 1805th of 2000 higher than 107 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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