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NCT01433757 · ClinicalTrials.gov registry record · Phase 1
Ampicillin for DYT-1 Dystonia Motor Symptoms
A Phase 1 study, sponsored by University of Florida.
- Completed
- Registry status
- Phase 1
- Development phase
- 2
- Enrollment target
NCT01433757: Completed Phase 1 study, sponsored by University of Florida.
NCT01433757 is a Phase 1 study that has completed, run by University of Florida. The registered enrollment target is 2 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01433757, a Phase 1 study, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 2 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate if the antibiotic Ampicillin is safe and tolerated in patients that have generalized dystonia caused by the DYT-1 gene mutation, as compared to patients treated with a placebo. A placebo is a pill that looks and tastes the same as the real drug, but without the active ingredient. The second objective of this study is to determine if dystonia symptoms improve while on the study drug.
Primary Outcome
The primary objective of this study is to evaluate the safety and tolerability of treating DYT-1 dystonia with the use of ampicillin as compared to placebo.
Interventions
- DRUG Ampicillin
- DRUG Sugar pill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2011-09 |
| Est. Completion | 2017-06 |
| Phase | Phase 1 |
What the finished NCT01433757 record still lists
NCT01433757 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Ampicillin is the first listed.
NCT01433757 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01433757 about?
NCT01433757 is a clinical study titled "Ampicillin for DYT-1 Dystonia Motor Symptoms". The purpose of this study is to evaluate if the antibiotic Ampicillin is safe and tolerated in patients that have generalized dystonia caused by the DYT-1 gene mutation, as compared to patients treated with a placebo. A placebo is a pill that looks and tastes the same as the real drug, but without t...
What is the current status of trial NCT01433757?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 2 participants. The study started on 2011-09. Estimated completion is 2017-06.
What interventions are being tested in trial NCT01433757?
The interventions under investigation include: Ampicillin (DRUG), Sugar pill (DRUG).
Who is sponsoring clinical trial NCT01433757?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01433757's enrollment target sits among peer trials
2 2000th of 2000 the lowest of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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