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NCT01431573 · ClinicalTrials.gov registry record · NA

Wake Therapy in the Treatment of Depression

A NA study, sponsored by New York State Psychiatric Institute.

Completed
Registry status
NA
Development phase
8
Enrollment target

NCT01431573: Completed NA study, sponsored by New York State Psychiatric Institute.

NCT01431573 is a NA study that has completed, run by New York State Psychiatric Institute. The registered enrollment target is 8 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01431573, a NA study, has completed, sponsored by New York State Psychiatric Institute.

COMPLETED
Registry status
NA
Development phase
8 participants
Enrollment target

Study Summary

This pilot study seeks to replicate previous findings that sleep deprivation results in marked improvement in depression symptoms, as well as to test whether concurrent treatment with Light Therapy and Lithium are successful in locking in and maintaining therapeutic effects in both bipolar and unipolar depressed subjects.

Primary Outcome

This is a structured interview to obtain 17 Hamilton Depression Rating Scale ratings, with 8 additional items added to measure reverse vegetative features common in bipolar depression and depression with atypical features. There are total 25 items, score ranges from 0 to 90. Higher score means worse depression.

Interventions

  • DRUG Lithium
  • BEHAVIORAL Wake Therapy
  • DEVICE light box

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2011-07
Est. Completion 2016-08
Phase NA

What the finished NCT01431573 record still lists

NCT01431573 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 3 interventions - of which Lithium is the first listed.

NCT01431573 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01431573 about?

NCT01431573 is a clinical study titled "Wake Therapy in the Treatment of Depression". This pilot study seeks to replicate previous findings that sleep deprivation results in marked improvement in depression symptoms, as well as to test whether concurrent treatment with Light Therapy and Lithium are successful in locking in and maintaining therapeutic effects in both bipolar and unipo...

What is the current status of trial NCT01431573?

This trial is currently completed. It is a NA study. The enrollment target is 8 participants. The study started on 2011-07. Estimated completion is 2016-08.

What interventions are being tested in trial NCT01431573?

The interventions under investigation include: Lithium (DRUG), Wake Therapy (BEHAVIORAL), light box (DEVICE).

Who is sponsoring clinical trial NCT01431573?

This trial is sponsored by New York State Psychiatric Institute, which has 364 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01431573's enrollment target sits among peer trials

8 1976th of 2000 higher than 19 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01431573, the US trial registry maintained by the National Library of Medicine. NCT01431573 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.