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NCT01427907 · ClinicalTrials.gov registry record · Phase 4

Equivalence of Calcium Acetate Oral Solution and Sevelamer Carbonate Tablets in Hemodialysis Patients

A Phase 4 study, sponsored by Fresenius Medical Care North America.

Completed
Registry status
Phase 4
Development phase
38
Enrollment target

NCT01427907: Completed Phase 4 study, sponsored by Fresenius Medical Care North America.

NCT01427907 is a Phase 4 study that has completed, run by Fresenius Medical Care North America. The registered enrollment target is 38 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01427907, a Phase 4 study, has completed, sponsored by Fresenius Medical Care North America.

COMPLETED
Registry status
Phase 4
Development phase
38 participants
Enrollment target

Study Summary

The purpose of this study is to demonstrate equivalence of calcium acetate oral solution and sevelamer carbonate in maintaining serum phosphorus levels This is a phase IV, multicenter, randomized, open-label, cross-over study to assess the equivalence of a liquid formulation of a calcium-based phosphate binder, COS, to sevelamer carbonate tablets, in hemodialysis dependent Chronic Kidney Disease subjects (CKD). The aim of the study is to maintain serum phosphorus level and establish equivalence between COS and sevelamer carbonate tablets.

Primary Outcome

The average phosphorus level of non-missing laboratory assessments from the last two weeks of each treatment period for each subject

Interventions

  • DRUG Sevelamer carbonate
  • DRUG Calcium acetate oral solution (COS)

Trial Details

FieldValue
Enrollment Target 38 participants
Start Date 2011-09
Est. Completion 2012-07
Phase Phase 4

What the finished NCT01427907 record still lists

NCT01427907 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 38 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (93% lower).

The record links to 0 conditions, and to 2 interventions - of which Sevelamer carbonate is the first listed.

NCT01427907 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01427907 about?

NCT01427907 is a clinical study titled "Equivalence of Calcium Acetate Oral Solution and Sevelamer Carbonate Tablets in Hemodialysis Patients". The purpose of this study is to demonstrate equivalence of calcium acetate oral solution and sevelamer carbonate in maintaining serum phosphorus levels This is a phase IV, multicenter, randomized, open-label, cross-over study to assess the equivalence of a liquid formulation of a calcium-based phos...

What is the current status of trial NCT01427907?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 38 participants. The study started on 2011-09. Estimated completion is 2012-07.

What interventions are being tested in trial NCT01427907?

The interventions under investigation include: Sevelamer carbonate (DRUG), Calcium acetate oral solution (COS) (DRUG).

Who is sponsoring clinical trial NCT01427907?

This trial is sponsored by Fresenius Medical Care North America, which has 13 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01427907's enrollment target sits among peer trials

38 1476th of 2000 higher than 519 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01427907, the US trial registry maintained by the National Library of Medicine. NCT01427907 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.