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NCT01426347 · ClinicalTrials.gov registry record · NA
Treatment of Vitamin D Deficiency in Patients With Rheumatoid Arthritis
A NA study, sponsored by Johns Hopkins University.
- Completed
- Registry status
- NA
- Development phase
- 139
- Enrollment target
NCT01426347: Completed NA study, sponsored by Johns Hopkins University.
NCT01426347 is a NA study that has completed, run by Johns Hopkins University. The registered enrollment target is 139 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01426347, a NA study, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- NA
- Development phase
- 139 participants
- Enrollment target
Study Summary
The purpose of this study is to investigate the effect of vitamin D repletion on disease activity and disability in patients with rheumatoid arthritis. The investigators hypothesize that rheumatoid arthritis (RA) patients with vitamin D deficiency have greater disease activity and disability, compared to RA patients with normal vitamin D levels. The investigators also hypothesize that vitamin D treatment in these deficient patients will result in a decrease in RA disease activity and disability.
Primary Outcome
We measured disease activity as measured by DAS 28 at baseline and at the completion of Randomized Controlled trial, both in the placebo and the active treatment group. We used DAS-28 scores to indicate disease activity. The DAS -28 scale has a minimum of 0 and a maximum of 10, with higher numbers indicating higher disease activity. We used the following cut-offs: Remission (\< 2.6), low disease activity (\< 3.2), moderate disease activity (\< 5.1) and high disease activity (\> 5.1).
Interventions
- DRUG Ergocalciferol
- DRUG Placebo sugar pill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 139 participants |
| Start Date | 2009-01 |
| Est. Completion | 2012-01 |
| Phase | NA |
What the finished NCT01426347 record still lists
NCT01426347 is an interventional study that assigns participants to a tested intervention. The registered 139 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 2 interventions - of which Ergocalciferol is the first listed.
NCT01426347 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01426347 about?
NCT01426347 is a clinical study titled "Treatment of Vitamin D Deficiency in Patients With Rheumatoid Arthritis". The purpose of this study is to investigate the effect of vitamin D repletion on disease activity and disability in patients with rheumatoid arthritis. The investigators hypothesize that rheumatoid arthritis (RA) patients with vitamin D deficiency have greater disease activity and disability, compa...
What is the current status of trial NCT01426347?
This trial is currently completed. It is a NA study. The enrollment target is 139 participants. The study started on 2009-01. Estimated completion is 2012-01.
What interventions are being tested in trial NCT01426347?
The interventions under investigation include: Ergocalciferol (DRUG), Placebo sugar pill (DRUG).
Who is sponsoring clinical trial NCT01426347?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01426347's enrollment target sits among peer trials
139 720th of 2000 higher than 1,281 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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