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NCT01426165 · ClinicalTrials.gov registry record · NA
Effect of Magnesium Sulfate Infusion Rate on Magnesium Retention in Critically Ill Patients
A NA study, sponsored by CAMC Health System.
- Terminated
- Registry status
- NA
- Development phase
- 5
- Enrollment target
NCT01426165: Clinical Trial NA study, sponsored by CAMC Health System.
NCT01426165 is a NA study that was terminated before completion, run by CAMC Health System. The registered enrollment target is 5 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01426165, a NA study, was terminated before completion, sponsored by CAMC Health System.
- TERMINATED
- Registry status
- NA
- Development phase
- 5 participants
- Enrollment target
Study Summary
Hypomagnesemia (low magnesium) is an electrolyte imbalance commonly found in up to 65% of critically ill patients. Possible consequences of hypomagnesemia include neuromuscular and neurologic dysfunction, heart arrhythmias, and alterations in other electrolytes. Data has shown that critically ill patients with hypomagnesemia have a significantly higher mortality rate than patients with a normal magnesium level. The most simple and commonly used test to diagnose hypomagnesemia is a serum magnesium level. Based on the magnesium level and symptoms of hypomagnesemia, patients may be replaced with either oral or intravenous (IV) magnesium. When replacing magnesium via the IV route, approximately half of the dose is retained by the body while the remainder is excreted in the urine. The low retention rate is due to the slow uptake of magnesium by cells and decreased magnesium reabsorption by the kidneys in response to the delivery of a large concentration of magnesium. The purpose of this study is to determine whether an eight hour compared to a four hour infusion of IV magnesium sulfate results in a greater retention of the magnesium dose.
Interventions
- DRUG Magnesium Sulfate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2011-04 |
| Est. Completion | 2012-12 |
| Phase | NA |
Why NCT01426165 stopped before completion
NCT01426165 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which Magnesium Sulfate is the first listed.
NCT01426165 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01426165 about?
NCT01426165 is a clinical study titled "Effect of Magnesium Sulfate Infusion Rate on Magnesium Retention in Critically Ill Patients". Hypomagnesemia (low magnesium) is an electrolyte imbalance commonly found in up to 65% of critically ill patients. Possible consequences of hypomagnesemia include neuromuscular and neurologic dysfunction, heart arrhythmias, and alterations in other electrolytes. Data has shown that critically ill pa...
What is the current status of trial NCT01426165?
This trial is currently terminated. It is a NA study. The enrollment target is 5 participants. The study started on 2011-04. Estimated completion is 2012-12.
What interventions are being tested in trial NCT01426165?
The interventions under investigation include: Magnesium Sulfate (DRUG).
Who is sponsoring clinical trial NCT01426165?
This trial is sponsored by CAMC Health System, which has 28 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01426165's enrollment target sits among peer trials
5 1988th of 2000 higher than 5 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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