Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01425385 · ClinicalTrials.gov registry record

Autoregulation Assessment During Liver Transplantation

A clinical trial, sponsored by Johns Hopkins University.

Completed
Registry status
10
Enrollment target

NCT01425385: Completed study, sponsored by Johns Hopkins University.

NCT01425385 is a clinical trial that has completed, run by Johns Hopkins University. The registered enrollment target is 10 participants. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist → Add completion date to calendar (.ics) →

The verdict

NCT01425385 has completed, sponsored by Johns Hopkins University.

COMPLETED
Registry status
10 participants
Enrollment target

Study Summary

Patients with liver failure undergoing liver transplantation often have clinical or sub-clinical encephalopathy that may lead to increased intracranial pressure. The latter may lead to abnormal regulation of blood flow to the brain (cerebral autoregulation) complicating patient management during and after general anesthesia. The current methods for monitoring for elevated intracranial pressure are invasive and, thus, limited to severe encephalopathy. In this study the investigators will evaluate the potential utility of monitoring cerebral blood flow (CBF) autoregulation non-invasively using near infra-red spectroscopy in patients undergoing liver transplantation.

Interventions

  • OTHER Near infrared spectroscopy monitoring
  • OTHER Autoregulation monitoring

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2011-09
Est. Completion 2012-09
Johns Hopkins University

1,448 total trials

What the finished NCT01425385 record still lists

NCT01425385 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 10 participants, a relatively small participant target.

The record links to 0 conditions, and to 2 interventions - of which Near infrared spectroscopy monitoring is the first listed.

NCT01425385 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01425385 about?

NCT01425385 is a clinical study titled "Autoregulation Assessment During Liver Transplantation". Patients with liver failure undergoing liver transplantation often have clinical or sub-clinical encephalopathy that may lead to increased intracranial pressure. The latter may lead to abnormal regulation of blood flow to the brain (cerebral autoregulation) complicating patient management during and...

What is the current status of trial NCT01425385?

This trial is currently completed. The enrollment target is 10 participants. The study started on 2011-09. Estimated completion is 2012-09.

What interventions are being tested in trial NCT01425385?

The interventions under investigation include: Near infrared spectroscopy monitoring (OTHER), Autoregulation monitoring (OTHER).

Who is sponsoring clinical trial NCT01425385?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00623389 · 10 participants · NA

    Evaluation of an Advanced Lower Extremity Neuroprostheses

  • NCT01241864 · 10 participants · Phase 2

    Islet Transplantation in Type 1 Diabetic Kidney Allograft

  • NCT01293214 · 10 participants · NA

    Vascularized Composite Allotransplantation for Multiple Extremity Amputations

  • NCT01474148 · 10 participants · NA

    A Neuroprosthesis for Seated Posture and Balance

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01425385, the US trial registry maintained by the National Library of Medicine. NCT01425385 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.