Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01419028 · ClinicalTrials.gov registry record

A Retrospective Study of the Natural History of Patients With Severe Perinatal and Infantile Hypophosphatasia (HPP)

A clinical trial of Hypophosphatasia (HPP), sponsored by Alexion Pharmaceuticals.

Completed
Registry status
48
Enrollment target
12
Study locations

NCT01419028: Completed study of Hypophosphatasia (HPP), sponsored by Alexion Pharmaceuticals.

NCT01419028 is a study of Hypophosphatasia (HPP) that has completed, run by Alexion Pharmaceuticals. The registered enrollment target is 48 participants. The trial reports 12 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01419028, a study of Hypophosphatasia (HPP), has completed, sponsored by Alexion Pharmaceuticals.

COMPLETED
Registry status
48 participants
Enrollment target
12
Study locations

Study Summary

This study aims to characterize the natural history of patients with severe perinatal or infantile onset HPP.

Primary Outcome

Overall survival is defined as the time from birth to time of death.

Conditions Studied

Study Locations (12)

Other

  • Royal Children's Hospital - Parkville
  • University of Manitoba Health Sciences Centre - Winnipeg
  • Universitatsmedizin Mainz, Villa - Mainz
  • Universitätsklinikum Würzburg Kinderklinik, Pädiatrische Infektiologie und Immunologie - Würzburg
  • Hospital Infantil Universitario Nino Jesus Universidad autonoma de Madrid - Madrid
  • National Taiwan University Hospital - Taipei
  • Birmingham Childrens Hospital - Birmingham

California

  • Cedars-Sinai Medical Center - Los Angeles

Indiana

  • Indiana University school of medicine - Indianapolis

Missouri

  • Shriners Hospital for Children - St Louis

Oregon

  • Oregon Health & Science University - Portland

Texas

  • Cook Children's Health Care System - Fort Worth

Trial Details

FieldValue
Enrollment Target 48 participants
Start Date 2012-08
Est. Completion 2014-02
Alexion Pharmaceuticals

162 total trials

What the finished NCT01419028 record still lists

NCT01419028 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 48 participants, a relatively small participant target.

The record links to 1 condition, with Hypophosphatasia (HPP) appearing as the primary indexed condition, and to 0 interventions.

NCT01419028 lists 12 locations in 6 states (Other, California, Indiana).

Frequently Asked Questions

What is clinical trial NCT01419028 about?

NCT01419028 is a clinical study titled "A Retrospective Study of the Natural History of Patients With Severe Perinatal and Infantile Hypophosphatasia (HPP)". This study aims to characterize the natural history of patients with severe perinatal or infantile onset HPP.

What is the current status of trial NCT01419028?

This trial is currently completed. The enrollment target is 48 participants. The study started on 2012-08. Estimated completion is 2014-02.

What conditions does trial NCT01419028 study?

This clinical trial studies the following conditions: Hypophosphatasia (HPP).

Who is sponsoring clinical trial NCT01419028?

This trial is sponsored by Alexion Pharmaceuticals, which has 162 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01419028 being conducted?

This trial has 12 study locations across California, Indiana, Missouri, Oregon, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01765777 · 48 participants · NA

    Efficacy of Osteopathic Manipulative Medicine (OMM) and Phototherapy for Patients With Chronic Lower Back Pain

  • NCT03073343 · 48 participants · NA

    A Prospective, Randomized, Open Label Trial of Two Doses of Oral Betaine

  • NCT03431064 · 48 participants

    Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients

  • NCT03514602 · 48 participants · NA

    Maternal Smoking Cessation and Pediatric Obesity Prevention

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01419028, the US trial registry maintained by the National Library of Medicine. NCT01419028 (small enrollment · multi site footprint · completed) retrieved and formatted by PlainTrial, see methodology.