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NCT01407939 · ClinicalTrials.gov registry record
Efficacy of Bitter Blockers on Taste Perception in Children and Adults
A clinical trial, sponsored by Monell Chemical Senses Center.
- Completed
- Registry status
- 215
- Enrollment target
NCT01407939: Completed study, sponsored by Monell Chemical Senses Center.
NCT01407939 is a clinical trial that has completed, run by Monell Chemical Senses Center. The registered enrollment target is 215 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01407939 has completed, sponsored by Monell Chemical Senses Center.
- COMPLETED
- Registry status
- 215 participants
- Enrollment target
Study Summary
This proposal describes 2 basic research studies that will be conducted sequentially. Study 1 will test the efficacy of both classic and newly developed "generally recognized as a safe" (GRAS) bitter blockers on the perceived bitterness and acceptance of different classes of bitter-tasting compounds by children and compare their responses to adults. Because variations among and between children and adults in terms of sensitivity to different bitter compounds are due in part to genetically determined receptor variation, the investigators will consider genotype when assessing how well bitter blockers perform. In Study 2, the investigators aim to evaluate different methods (forced-choice procedures, hedonic face scales) used for testing children to determine their reliability and reproducibility.
Primary Outcome
Primary outcome variables are the proportion of subjects by age group (children and adults) judging a variety of GRAS bitter compounds with a bitter blocker as less bitter or more pleasant than the bitter compound alone (the efficacy of the bitter blocker). At least 5 bitter compounds and 5 GRAS bitter blockers will be used. We will determine how these measures are affected by the age and genotype of the subjects.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 215 participants |
| Start Date | 2011-04 |
| Est. Completion | 2016-03 |
What the finished NCT01407939 record still lists
NCT01407939 is an observational study that tracks outcomes without assigning an intervention. The registered 215 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT01407939 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01407939 about?
NCT01407939 is a clinical study titled "Efficacy of Bitter Blockers on Taste Perception in Children and Adults". This proposal describes 2 basic research studies that will be conducted sequentially. Study 1 will test the efficacy of both classic and newly developed "generally recognized as a safe" (GRAS) bitter blockers on the perceived bitterness and acceptance of different classes of bitter-tasting compounds...
What is the current status of trial NCT01407939?
This trial is currently completed. The enrollment target is 215 participants. The study started on 2011-04. Estimated completion is 2016-03.
Who is sponsoring clinical trial NCT01407939?
This trial is sponsored by Monell Chemical Senses Center, which has 16 total clinical trials registered on ClinicalTrials.gov.
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