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NCT01406847 · ClinicalTrials.gov registry record · NA
Central Mechanisms of Intervention for Low Back Pain
A NA study, sponsored by University of Florida.
- Completed
- Registry status
- NA
- Development phase
- 159
- Enrollment target
NCT01406847: Completed NA study, sponsored by University of Florida.
NCT01406847 is a NA study that has completed, run by University of Florida. The registered enrollment target is 159 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01406847, a NA study, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- NA
- Development phase
- 159 participants
- Enrollment target
Study Summary
Body-based interventions have consistently shown clinical effectiveness in patients with back pain. The primary objective for this study is to compare the effect of body-based interventions commonly used in the management of low back pain on behavioral and cortical measures of pain sensitivity and central sensitization of pain. Participants will be randomly assigned to receive one of the interventions or be in a control group. The central hypothesis for this proposal is that spinal manipulation, a specific form of body-based intervention, inhibits central sensitization of pain normalizing pain sensitivity more rapidly than other interventions. The completion of the proposed study will elucidate underpinning mechanisms of body-based interventions. Identification of these mechanisms will improve the clinical application and utilization of these interventions in the management of musculoskeletal pain conditions, especially back pain.
Primary Outcome
We will use both behavioral (ratings) and cortical (using fMRI) measures of temporal sensory summation.
Interventions
- OTHER Spinal Manipulation
- OTHER Spinal Mobilization
- OTHER Static Touch
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 159 participants |
| Start Date | 2012-08 |
| Est. Completion | 2017-05-01 |
| Phase | NA |
What the finished NCT01406847 record still lists
NCT01406847 is an interventional study that assigns participants to a tested intervention. The registered 159 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (89% lower).
The record links to 0 conditions, and to 3 interventions - of which Spinal Manipulation is the first listed.
NCT01406847 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01406847 about?
NCT01406847 is a clinical study titled "Central Mechanisms of Intervention for Low Back Pain". Body-based interventions have consistently shown clinical effectiveness in patients with back pain. The primary objective for this study is to compare the effect of body-based interventions commonly used in the management of low back pain on behavioral and cortical measures of pain sensitivity and c...
What is the current status of trial NCT01406847?
This trial is currently completed. It is a NA study. The enrollment target is 159 participants. The study started on 2012-08. Estimated completion is 2017-05-01.
What interventions are being tested in trial NCT01406847?
The interventions under investigation include: Spinal Manipulation (OTHER), Spinal Mobilization (OTHER), Static Touch (OTHER).
Who is sponsoring clinical trial NCT01406847?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01406847's enrollment target sits among peer trials
159 654th of 2000 higher than 1,347 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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