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NCT01402063 · ClinicalTrials.gov registry record · Phase 2

PPX and Concurrent Radiation for Newly Diagnosed Glioblastoma Without MGMT Methylation

A Phase 2 study of Glioblastoma Multiforme, sponsored by Brown University.

Completed
Registry status
Phase 2
Development phase
63
Enrollment target
9
Study locations

NCT01402063 is a Phase 2 study of Glioblastoma Multiforme that has completed, run by Brown University. The registered enrollment target is 63 participants, below the 96-participant average among 88 other Glioblastoma Multiforme trials with a reported enrollment target (34% lower). The trial reports 9 study locations across 8 states.

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The verdict

NCT01402063, a Phase 2 study of Glioblastoma Multiforme, has completed, sponsored by Brown University.

COMPLETED
Registry status
Phase 2
Development phase
63 participants
Enrollment target
9
Study locations

Study Summary

To obtain preliminary data in a randomized phase II study whether PPX/RT improves progression-free survival as compared to temozolomide/RT for patients with GBM without MGMT methylation.

Conditions Studied

Interventions

  • DRUG Temozolomide
  • DRUG PPX (CT2103)

Study Locations (9)

Pennsylvania

  • PSU - Hershey
  • Thomas Jefferson University Cancer Center - Philadelphia

California

  • UCSD Cancer Center - La Jolla

Maine

  • Maine Medical Center - Scarborough

Massachusetts

  • UMASS Medical Center Cancer Center - Worcester

New York

  • SUNY Medical Center - Syracuse

Rhode Island

  • Rhode Island Hospital - Providence

Texas

  • UT Southwestern Cancer Center - Dallas

Washington

  • University of Washington - Seattle

Trial Details

FieldValue
Enrollment Target 63 participants
Start Date 2011-09
Est. Completion 2015-06
Phase Phase 2

Sponsor

Brown University

231 total trials

What the Registry Record Tells You About NCT01402063

The ClinicalTrials.gov registry entry for NCT01402063 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 63 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 96-participant average among 88 other Glioblastoma Multiforme trials with a reported enrollment target (34% lower). The listed sponsor is Brown University, which has 231 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Glioblastoma Multiforme appearing as the primary indexed condition, and to 2 interventions - of which Temozolomide is the first listed.

NCT01402063 reports 9 study locations spanning 8 distinct geographic areas - top geographies include Pennsylvania, California, Maine.

Frequently Asked Questions

What is clinical trial NCT01402063 about?

NCT01402063 is a clinical study titled "PPX and Concurrent Radiation for Newly Diagnosed Glioblastoma Without MGMT Methylation". To obtain preliminary data in a randomized phase II study whether PPX/RT improves progression-free survival as compared to temozolomide/RT for patients with GBM without MGMT methylation.

What is the current status of trial NCT01402063?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 63 participants. The study started on 2011-09. Estimated completion is 2015-06.

What conditions does trial NCT01402063 study?

This clinical trial studies the following conditions: Glioblastoma Multiforme.

What interventions are being tested in trial NCT01402063?

The interventions under investigation include: Temozolomide (DRUG), PPX (CT2103) (DRUG).

Who is sponsoring clinical trial NCT01402063?

This trial is sponsored by Brown University, which has 231 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01402063 being conducted?

This trial has 9 study locations across California, Maine, Massachusetts, New York, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.