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NCT01399684 · ClinicalTrials.gov registry record · Phase 2

A Study Evaluating the Efficacy and Safety of MEGF0444A Dosed to Progression in Combination With Bevacizumab and mFOLFOX-6 in Participants With Previously Untreated Metastatic Colorectal Cancer

A Phase 2 study, sponsored by Genentech.

Completed
Registry status
Phase 2
Development phase
127
Enrollment target

NCT01399684 is a Phase 2 study that has completed, run by Genentech. The registered enrollment target is 127 participants.

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The verdict

NCT01399684, a Phase 2 study, has completed, sponsored by Genentech.

COMPLETED
Registry status
Phase 2
Development phase
127 participants
Enrollment target

Study Summary

This is a Phase II, multicenter, randomized, double-blind, placebo-controlled trial designed to estimate the efficacy of MEGF0444A treatment to disease progression, combined with oxaliplatin + folinic acid + 5-Fluorouracil (mFOLFOX-6) + bevacizumab therapy in participants with metastatic colorectal cancer (CRC).

Interventions

  • DRUG Bevacizumab
  • DRUG Oxaliplatin
  • DRUG 5-Fluorouracil
  • DRUG Folinic acid
  • DRUG MEGF0444A

Trial Details

FieldValue
Enrollment Target 127 participants
Start Date 2011-11
Est. Completion 2014-02
Phase Phase 2

Sponsor

Genentech

332 total trials

What the Registry Record Tells You About NCT01399684

The ClinicalTrials.gov registry entry for NCT01399684 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 127 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Genentech, which has 332 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Bevacizumab is the first listed.

NCT01399684 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01399684 about?

NCT01399684 is a clinical study titled "A Study Evaluating the Efficacy and Safety of MEGF0444A Dosed to Progression in Combination With Bevacizumab and mFOLFOX-6 in Participants With Previously Untreated Metastatic Colorectal Cancer". This is a Phase II, multicenter, randomized, double-blind, placebo-controlled trial designed to estimate the efficacy of MEGF0444A treatment to disease progression, combined with oxaliplatin + folinic acid + 5-Fluorouracil (mFOLFOX-6) + bevacizumab therapy in participants with metastatic colorectal ...

What is the current status of trial NCT01399684?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 127 participants. The study started on 2011-11. Estimated completion is 2014-02.

What interventions are being tested in trial NCT01399684?

The interventions under investigation include: Bevacizumab (DRUG), Oxaliplatin (DRUG), 5-Fluorouracil (DRUG), Folinic acid (DRUG), MEGF0444A (DRUG).

Who is sponsoring clinical trial NCT01399684?

This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.