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NCT01390181 · ClinicalTrials.gov registry record · NA
The Effect of Losartan in Bicuspid Aortic Valve Patients
A NA study, sponsored by University of Michigan.
- Terminated
- Registry status
- NA
- Development phase
- 4
- Enrollment target
NCT01390181 is a NA study that was terminated before completion, run by University of Michigan. The registered enrollment target is 4 participants.
The verdict
NCT01390181, a NA study, was terminated before completion, sponsored by University of Michigan.
- TERMINATED
- Registry status
- NA
- Development phase
- 4 participants
- Enrollment target
Study Summary
The specific aims of this study are to: * Establish baseline levels of circulating MMP-2 and -9 , TIMP-1and- 2 and TGFB levels in individuals with bicuspid aortic valve and ascending aortic or aortic sinus measurements \>40mm. * Assess the effect on MMP levels during treatment with losartan, an angiotensin II receptor blocking agent. * In the setting of losartan therapy for one year, evaluate the response of MMP levels in these patients, and clinical outcomes including effects on aortic growth rate
Interventions
- DRUG Cozaar
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2011-09 |
| Est. Completion | 2014-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01390181
The ClinicalTrials.gov registry entry for NCT01390181 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 4 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Michigan, which has 1,327 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Cozaar is the first listed.
NCT01390181 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01390181 about?
NCT01390181 is a clinical study titled "The Effect of Losartan in Bicuspid Aortic Valve Patients". The specific aims of this study are to: * Establish baseline levels of circulating MMP-2 and -9 , TIMP-1and- 2 and TGFB levels in individuals with bicuspid aortic valve and ascending aortic or aortic sinus measurements \>40mm. * Assess the effect on MMP levels during treatment with losartan, an ang...
What is the current status of trial NCT01390181?
This trial is currently terminated. It is a NA study. The enrollment target is 4 participants. The study started on 2011-09. Estimated completion is 2014-01.
What interventions are being tested in trial NCT01390181?
The interventions under investigation include: Cozaar (DRUG).
Who is sponsoring clinical trial NCT01390181?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
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