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NCT01388478 · ClinicalTrials.gov registry record · Phase 2
Safety Study of R(+)Pramipexole to Treat Early Alzheimer's Disease
A Phase 2 study, sponsored by Virginia Commonwealth University.
- Completed
- Registry status
- Phase 2
- Development phase
- 20
- Enrollment target
NCT01388478: Completed Phase 2 study, sponsored by Virginia Commonwealth University.
NCT01388478 is a Phase 2 study that has completed, run by Virginia Commonwealth University. The registered enrollment target is 20 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01388478, a Phase 2 study, has completed, sponsored by Virginia Commonwealth University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 20 participants
- Enrollment target
Study Summary
By doing this study, researchers will examine the safety and tolerability of R-pramipexole in participants with Alzheimer's disease. This study will also examine the body and brain's response to the study drug by measuring the amount of injury to the cells (oxidative stress) in the blood and spinal fluid and brain imaging before and after treatment.
Primary Outcome
Labwork will be performed every two months. There will be frequent contact with subjects to assess for adverse events.
Interventions
- DRUG R-pramipexole
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2011-07 |
| Est. Completion | 2014-04 |
| Phase | Phase 2 |
What the finished NCT01388478 record still lists
NCT01388478 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower).
The record links to 0 conditions, and to 1 intervention - of which R-pramipexole is the first listed.
NCT01388478 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01388478 about?
NCT01388478 is a clinical study titled "Safety Study of R(+)Pramipexole to Treat Early Alzheimer's Disease". By doing this study, researchers will examine the safety and tolerability of R-pramipexole in participants with Alzheimer's disease. This study will also examine the body and brain's response to the study drug by measuring the amount of injury to the cells (oxidative stress) in the blood and spinal ...
What is the current status of trial NCT01388478?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2011-07. Estimated completion is 2014-04.
What interventions are being tested in trial NCT01388478?
The interventions under investigation include: R-pramipexole (DRUG).
Who is sponsoring clinical trial NCT01388478?
This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01388478's enrollment target sits among peer trials
20 1805th of 2000 higher than 107 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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