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NCT01383447 · ClinicalTrials.gov registry record · Phase 1

Entinostat And Imatinib Mesylate In Treating Patients With Relapsed or Refractory Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

A Phase 1 study, sponsored by National Cancer Institute (NCI).

Terminated
Registry status
Phase 1
Development phase
2
Enrollment target

NCT01383447: Clinical Trial Phase 1 study, sponsored by National Cancer Institute (NCI).

NCT01383447 is a Phase 1 study that was terminated before completion, run by National Cancer Institute (NCI). The registered enrollment target is 2 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01383447, a Phase 1 study, was terminated before completion, sponsored by National Cancer Institute (NCI).

TERMINATED
Registry status
Phase 1
Development phase
2 participants
Enrollment target

Study Summary

This phase I/II trial is studying the side effects and best dose of entinostat when given together with imatinib mesylate and to see how well it works in treating patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia. Entinostat and imatinib mesylate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth

Interventions

  • OTHER laboratory biomarker analysis
  • DRUG imatinib mesylate
  • OTHER pharmacological study
  • GENETIC western blotting
  • DRUG entinostat

Trial Details

FieldValue
Enrollment Target 2 participants
Start Date 2010-10
Est. Completion 2012-04
Phase Phase 1

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT01383447

The ClinicalTrials.gov registry entry for NCT01383447 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 2 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which laboratory biomarker analysis is the first listed.

NCT01383447 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01383447 about?

NCT01383447 is a clinical study titled "Entinostat And Imatinib Mesylate In Treating Patients With Relapsed or Refractory Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia". This phase I/II trial is studying the side effects and best dose of entinostat when given together with imatinib mesylate and to see how well it works in treating patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia. Entinostat and imatinib mesylate may ...

What is the current status of trial NCT01383447?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 2 participants. The study started on 2010-10. Estimated completion is 2012-04.

What interventions are being tested in trial NCT01383447?

The interventions under investigation include: laboratory biomarker analysis (OTHER), imatinib mesylate (DRUG), pharmacological study (OTHER), western blotting (GENETIC), entinostat (DRUG).

Who is sponsoring clinical trial NCT01383447?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.