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NCT01377636 · ClinicalTrials.gov registry record · NA
Measurement of Bispectral Index and Awareness in Patients Undergoing Electrophysiology Studies With Isoproterenol
A NA study, sponsored by NYU Langone Health.
- Completed
- Registry status
- NA
- Development phase
- 20
- Enrollment target
NCT01377636: Completed NA study, sponsored by NYU Langone Health.
NCT01377636 is a NA study that has completed, run by NYU Langone Health. The registered enrollment target is 20 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01377636, a NA study, has completed, sponsored by NYU Langone Health.
- COMPLETED
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
Study Summary
Isoproterenol is used as a cardiac stimulant in electrophysiology studies (EP). Preliminary data suggests that administration of isoproterenol increases the Bispectral index (BIS). BIS is used to monitor neuronal signals under anesthesia. The BIS level is suggested to correspond to the level of consciousness. We hypothesize that isoproterenol increases BIS values because it increases the patient's level of consciousness through its central nervous system (CNS) stimulatory effects. In this study, we will administer increasing doses of isoproterenol to EPS patients. We will measure the BIS levels continuously before and after isoproterenol administration. In addition, we will test the level of awareness of patients by their response to a modified isolated forearm technique.
Primary Outcome
Increasing doses of isoproterenol (5,10,15,20 mcg/minute) were administered to patients undergoing catheter ablation for atrial fibrillation. BIS levels were measured continuously before and after isoproterenol administration. Number of participants with increase in BIS reading during anesthetic steady state are reported below. The BIS scale ranges from 0 to 100. The individual's baseline BIS was measured continuously and was maintained in an anesthetic steady state with minimum variance prior t
Interventions
- DRUG Isoproterenol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2009-08 |
| Est. Completion | 2011-10 |
| Phase | NA |
What the finished NCT01377636 record still lists
NCT01377636 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Isoproterenol is the first listed.
NCT01377636 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01377636 about?
NCT01377636 is a clinical study titled "Measurement of Bispectral Index and Awareness in Patients Undergoing Electrophysiology Studies With Isoproterenol". Isoproterenol is used as a cardiac stimulant in electrophysiology studies (EP). Preliminary data suggests that administration of isoproterenol increases the Bispectral index (BIS). BIS is used to monitor neuronal signals under anesthesia. The BIS level is suggested to correspond to the level of cons...
What is the current status of trial NCT01377636?
This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2009-08. Estimated completion is 2011-10.
What interventions are being tested in trial NCT01377636?
The interventions under investigation include: Isoproterenol (DRUG).
Who is sponsoring clinical trial NCT01377636?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01377636's enrollment target sits among peer trials
20 1768th of 2000 higher than 140 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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