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NCT01367561 · ClinicalTrials.gov registry record · Phase 1

Naloxone and Intravenous Methylnaltrexone Effects on Bladder Function

A Phase 1 study of Healthy Males, sponsored by Bausch Health Americas.

Completed
Registry status
Phase 1
Development phase
15
Enrollment target
1
Study location

NCT01367561: Completed Phase 1 study of Healthy Males, sponsored by Bausch Health Americas.

NCT01367561 is a Phase 1 study of Healthy Males that has completed, run by Bausch Health Americas. The registered enrollment target is 15 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01367561, a Phase 1 study of Healthy Males, has completed, sponsored by Bausch Health Americas.

COMPLETED
Registry status
Phase 1
Development phase
15 participants
Enrollment target
1
Study location

Study Summary

This is a double-blind, randomized, study at a single clinical site investigating the effect of methylnaltrexone and naloxone versus placebo in healthy males who have received a short-acting opioid, remifentanil.

Primary Outcome

To investigate the potential benefit of methylnaltrexone in preventing or treating opioid-induced urinary retention.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Naloxone
  • DRUG IV Methylnaltrexone (MNTX)

Study Locations (1)

New York

  • Progenics Pharmaceuticals, Inc. - Tarrytown

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2002-10
Est. Completion 2003-05
Phase Phase 1
Bausch Health Americas

168 total trials

What the finished NCT01367561 record still lists

NCT01367561 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower).

The record links to 1 condition, with Healthy Males appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT01367561 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT01367561 about?

NCT01367561 is a clinical study titled "Naloxone and Intravenous Methylnaltrexone Effects on Bladder Function". This is a double-blind, randomized, study at a single clinical site investigating the effect of methylnaltrexone and naloxone versus placebo in healthy males who have received a short-acting opioid, remifentanil.

What is the current status of trial NCT01367561?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2002-10. Estimated completion is 2003-05.

What conditions does trial NCT01367561 study?

This clinical trial studies the following conditions: Healthy Males.

What interventions are being tested in trial NCT01367561?

The interventions under investigation include: Placebo (DRUG), Naloxone (DRUG), IV Methylnaltrexone (MNTX) (DRUG).

Who is sponsoring clinical trial NCT01367561?

This trial is sponsored by Bausch Health Americas, which has 168 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01367561 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Healthy Males

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01367561's enrollment target sits among peer trials

15 1798th of 2000 higher than 157 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01367561, the US trial registry maintained by the National Library of Medicine. NCT01367561 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.