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NCT01366924 · ClinicalTrials.gov registry record · Phase 1

Essential Amino Acids Supplementation and Muscle Protein Synthesis

A Phase 1 study, sponsored by United States Army Research Institute of Environmental Medicine.

Completed
Registry status
Phase 1
Development phase
23
Enrollment target

NCT01366924: Completed Phase 1 study, sponsored by United States Army Research Institute of Environmental Medicine.

NCT01366924 is a Phase 1 study that has completed, run by United States Army Research Institute of Environmental Medicine. The registered enrollment target is 23 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01366924, a Phase 1 study, has completed, sponsored by United States Army Research Institute of Environmental Medicine.

COMPLETED
Registry status
Phase 1
Development phase
23 participants
Enrollment target

Study Summary

The modern warfighter faces numerous physiological challenges including sleep deprivation, sustained intense physical activity, and caloric restriction, the combined effects of which may result in the loss of lean body mass and decreased physical performance. Dietary interventions may help preserve lean body mass and facilitate recovery from periods of intense physical demand. For example, dietary strategies that increase amino acid availability have been shown to stimulate protein synthesis in skeletal muscle following resistance exercise. Because military tasks also incorporate endurance exercise components, studies regarding the effects of increasing dietary amino acids following endurance exercise are warranted. The objectives of this study are to characterize the effect of endurance exercise on protein synthesis and breakdown as well as the ability of an essential amino acid supplement to influence skeletal muscle protein metabolism and its cellular and molecular regulation following endurance exercise.

Interventions

  • DIETARY_SUPPLEMENT Essential Amino Acids
  • OTHER Endurance exercise

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2007-05
Est. Completion 2010-07
Phase Phase 1

What the finished NCT01366924 record still lists

NCT01366924 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (62% lower).

The record links to 0 conditions, and to 2 interventions - of which Essential Amino Acids is the first listed.

NCT01366924 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01366924 about?

NCT01366924 is a clinical study titled "Essential Amino Acids Supplementation and Muscle Protein Synthesis". The modern warfighter faces numerous physiological challenges including sleep deprivation, sustained intense physical activity, and caloric restriction, the combined effects of which may result in the loss of lean body mass and decreased physical performance. Dietary interventions may help preserve ...

What is the current status of trial NCT01366924?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 23 participants. The study started on 2007-05. Estimated completion is 2010-07.

What interventions are being tested in trial NCT01366924?

The interventions under investigation include: Essential Amino Acids (DIETARY_SUPPLEMENT), Endurance exercise (OTHER).

Who is sponsoring clinical trial NCT01366924?

This trial is sponsored by United States Army Research Institute of Environmental Medicine, which has 59 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01366924's enrollment target sits among peer trials

23 1596th of 2000 higher than 400 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01366924, the US trial registry maintained by the National Library of Medicine. NCT01366924 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.