Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01366716 · ClinicalTrials.gov registry record · NA

Contingency Management for Cocaine Dependence: Cash Versus Vouchers

A NA study, sponsored by Treatment Research Institute.

Completed
Registry status
NA
Development phase
352
Enrollment target

NCT01366716: Completed NA study, sponsored by Treatment Research Institute.

NCT01366716 is a NA study that has completed, run by Treatment Research Institute. The registered enrollment target is 352 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (75% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01366716, a NA study, has completed, sponsored by Treatment Research Institute.

COMPLETED
Registry status
NA
Development phase
352 participants
Enrollment target

Study Summary

Contingency management (CM) is a demonstrably efficacious intervention for substance abuse and dependence. Although CM protocols have employed a variety of reinforcers, they have almost exclusively relied upon non-cash privileges (e.g., take-home methadone doses), prizes, or vouchers that can be exchanged for goods or services. Despite the strong empirical support for CM, our research suggests that concerns relating to its cost and safety (e.g., potential for harm caused by rewards undermining intrinsic motivation or being sold to purchase drugs) have hindered its transfer to real-world practice. The exclusive use of non-cash CM likely stems from the untested assumption that clients will use cash incentives to buy drugs or engage in other high-risk behaviors. This assumption is problematic for two reasons. First, the use of non-cash incentives may add substantial costs and complexity to CM protocols. Second, the use of non-cash incentives may reduce the efficacy of CM interventions, as research suggests that cash may be a more effective reinforcer than vouchers. This study examines both practical and ethical issues relating to cash-based CM procedures. This study consists of three phases; a main experiment, a "Cash Bowl" pilot, and a "Thinning" Pilot.

Primary Outcome

Determine the differential efficacy of cash CM, voucher CM and standard (non-CM) outpatient treatment in improving during-treatment and post-treatment outcomes (i.e., drug abstinence, treatment attendance, and reduction in psychosocial problems) among cocaine-dependent outpatients in community-based treatment.

Interventions

  • BEHAVIORAL Cash CM
  • BEHAVIORAL Voucher CM

Trial Details

FieldValue
Enrollment Target 352 participants
Start Date 2008-04
Est. Completion 2013-06
Phase NA
Treatment Research Institute

18 total trials

What the finished NCT01366716 record still lists

NCT01366716 is an interventional study that assigns participants to a tested intervention. The registered 352 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (75% lower).

The record links to 0 conditions, and to 2 interventions - of which Cash CM is the first listed.

NCT01366716 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01366716 about?

NCT01366716 is a clinical study titled "Contingency Management for Cocaine Dependence: Cash Versus Vouchers". Contingency management (CM) is a demonstrably efficacious intervention for substance abuse and dependence. Although CM protocols have employed a variety of reinforcers, they have almost exclusively relied upon non-cash privileges (e.g., take-home methadone doses), prizes, or vouchers that can be exc...

What is the current status of trial NCT01366716?

This trial is currently completed. It is a NA study. The enrollment target is 352 participants. The study started on 2008-04. Estimated completion is 2013-06.

What interventions are being tested in trial NCT01366716?

The interventions under investigation include: Cash CM (BEHAVIORAL), Voucher CM (BEHAVIORAL).

Who is sponsoring clinical trial NCT01366716?

This trial is sponsored by Treatment Research Institute, which has 18 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01366716's enrollment target sits among peer trials

352 292nd of 2000 higher than 1,709 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT05811936 · 352 participants · NA

    The SNAP Tool for Head and Neck Cancer Survivor-Caregiver Dyads

  • NCT06258941 · 352 participants · Phase 1

    Classroom Break, Cognition, and Fitness in Elementary School Children

  • NCT06269081 · 352 participants · NA

    Testing Two Interventions to Improve Health Outcomes and Quality of Life Among Rural Older Adults Living With HIV

  • NCT06337292 · 352 participants · Phase 3

    Incisional Negative Pressure Wound Therapy to Reduce Infection and Complications in High-Risk Fractures

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01366716, the US trial registry maintained by the National Library of Medicine. NCT01366716 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.