Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01366534 · ClinicalTrials.gov registry record · Phase 2
Safety, Immunogenicity and Efficacy Against of a Combined Malaria Vaccine in Healthy Malaria-naïve Adults
A Phase 2 study of Malaria, sponsored by GlaxoSmithKline.
- Completed
- Registry status
- Phase 2
- Development phase
- 67
- Enrollment target
- 1
- Study location
NCT01366534 is a Phase 2 study of Malaria that has completed, run by GlaxoSmithKline. The registered enrollment target is 67 participants, below the 256-participant average among 27 other Malaria trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state.
The verdict
NCT01366534, a Phase 2 study of Malaria, has completed, sponsored by GlaxoSmithKline.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 67 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will evaluate whether administration of two investigational malaria vaccines (257049 and Ad35.CS.01 vaccines) combined in one immunization schedule increases protection against malaria infection as compared to protection induced by the 257049 vaccine alone. The study will also evaluate the safety and the immune response to the new combination of the two experimental malaria vaccines.
Conditions Studied
Interventions
- BIOLOGICAL Crucell's replication deficient adenovirus type 35 circumsporozoite malaria vaccine (Ad35.CS.01)
- BIOLOGICAL GSK Biologicals' malaria vaccine 257049 (2 doses)
- BIOLOGICAL GSK Biologicals' malaria vaccine 257049 (3 doses)
- OTHER Sporozoite challenge
Study Locations (1)
Maryland
- GSK Investigational Site - Silver Spring
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 67 participants |
| Start Date | 2011-08-10 |
| Est. Completion | 2012-07-03 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01366534
The ClinicalTrials.gov registry entry for NCT01366534 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 67 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 256-participant average among 27 other Malaria trials with a reported enrollment target (74% lower). The listed sponsor is GlaxoSmithKline, which has 1,345 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Malaria appearing as the primary indexed condition, and to 4 interventions - of which Crucell's replication deficient adenovirus type 35 circumsporozoite malaria vaccine (Ad35.CS.01) is the first listed.
NCT01366534 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT01366534 about?
NCT01366534 is a clinical study titled "Safety, Immunogenicity and Efficacy Against of a Combined Malaria Vaccine in Healthy Malaria-naïve Adults". This study will evaluate whether administration of two investigational malaria vaccines (257049 and Ad35.CS.01 vaccines) combined in one immunization schedule increases protection against malaria infection as compared to protection induced by the 257049 vaccine alone. The study will also evaluate th...
What is the current status of trial NCT01366534?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 67 participants. The study started on 2011-08-10. Estimated completion is 2012-07-03.
What conditions does trial NCT01366534 study?
This clinical trial studies the following conditions: Malaria.
What interventions are being tested in trial NCT01366534?
The interventions under investigation include: Crucell's replication deficient adenovirus type 35 circumsporozoite malaria vaccine (Ad35.CS.01) (BIOLOGICAL), GSK Biologicals' malaria vaccine 257049 (2 doses) (BIOLOGICAL), GSK Biologicals' malaria vaccine 257049 (3 doses) (BIOLOGICAL), Sporozoite challenge (OTHER).
Who is sponsoring clinical trial NCT01366534?
This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01366534 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Malaria
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Weekly Dosing of Malarone ® for Prevention of Malaria
COMPLETED · Phase 2
-
Efficacy, Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Evaluating Different Dose Schedules in a Sporozoite Challenge Model in Healthy Malaria-naïve Adults
COMPLETED · Phase 2
-
Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge
RECRUITING
-
Observational Study of the Safety of Intravenous Artesunate Treatment of Pregnant Women and Their Infants
RECRUITING
-
Evaluation, Treatment and Monitoring of Patients With a Known or Suspected Parasitic Infection
RECRUITING
-
A Study of Oral E1018 in Healthy Adult Participants
RECRUITING · Phase 1
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.